Sildenafil
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- ₹10041.5
- Product name: Sildenafil
- CAS: 139755-83-2
- MF: C22H30N6O4S
- MW: 474.58
- EINECS:604-158-7
- MDL Number:MFCD00867528
- Synonyms:SILDENAFIL;7H-Pyrazolo[4,3-d]pyriMidin-7-one, 5-[2-ethoxy-5-[(4-Methyl -1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-Methyl-3-propyl-;Sildenafil solution;5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d] pyrimidin-7-one;5-[2-Ethoxy-5-[(4-methyl-piperazin-1-yl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;5-(2-Ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one;5-[2-ethoxy-5-(4-Methylpiperazine-1-sulfonyl)phenyl]-1-Methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyriMidin-7-one;1-[[3-(4,7-Dihydro-1-Methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyriMidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-Methylpiperazine
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1ML
- ManufacturerSigma-Aldrich(India)
- Product numberS-010
- Product descriptionSildenafil solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging1ML
- Price₹10041.5
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S-010 | Sildenafil solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 1ML | ₹10041.5 | 2022-06-14 | Buy |
Properties
Melting point :187-189°C
Density :1.39±0.1 g/cm3(Predicted)
Flash point :9℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :pKa 8.7 (Uncertain)
color :White to Off-White
InChIKey :BNRNXUUZRGQAQC-UHFFFAOYSA-N
CAS DataBase Reference :139755-83-2(CAS DataBase Reference)
EPA Substance Registry System :7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl- (139755-83-2)
Density :1.39±0.1 g/cm3(Predicted)
Flash point :9℃
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :pKa 8.7 (Uncertain)
color :White to Off-White
InChIKey :BNRNXUUZRGQAQC-UHFFFAOYSA-N
CAS DataBase Reference :139755-83-2(CAS DataBase Reference)
EPA Substance Registry System :7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl- (139755-83-2)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Sildenafil was launched as Viagra in the US for the treatment of organic orland psychological male erectile dysfunction (ED). It is an orally bioavailable pyrazolopyrimidinone derivative structurally related to zaprinast, with vasodilating and potential anti-inflammatory activities. Upon oral administration, sildenafil selectively targets and inhibits cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), thereby inhibiting the PDE5-mediated degradation of cGMP found in smooth muscle and increasing cGMP availability. This results in prolonged smooth muscle relaxation in the corpus cavernosum of the penis, thereby causing vasodilation, blood engorgement and a prolonged penile erection.More related product prices
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