DL-Mevalonolactone
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- ₹3200 - ₹51678.55
- Product name: DL-Mevalonolactone
- CAS: 674-26-0
- MF: C6H10O3
- MW: 130.14
- EINECS:211-615-0
- MDL Number:MFCD00006648
- Synonyms:DL-MEVALONOLACTONE;β-Hydroxy-β-methyl-δ-valerolactone, (±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, (±)-Mevalolactone, (±)-Mevalonic acid lactone, (±)-Mevalonolactone;(4S)-4-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-3,5-Dihydroxy-3-methylpentanoic acid δ-lactone;(S)-4β-Hydroxy-4-methyltetrahydro-2H-pyran-2-one;(S)-Tetrahydro-4-hydroxy-4-methyl-2H-pyran-2-one;Beta-Hydro;(±)-Mevalonolactone,(±)-β-Hydroxy-β-methyl-δ-valerolactone, (±)-3-Hydroxy-3-methyl δ-valerolactone, DL-Mevalolactone, DL-Mevalonic acid lactone
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 100MG
- 1G
- 5G
- 10G
- ManufacturerTCI Chemicals (India)
- Product numberD0587
- Product descriptionDL-Mevalonolactone min. 98.0 %
- Packaging100MG
- Price₹3200
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4667
- Product description(±)-Mevalonolactone ~97% (titration)
- Packaging10G
- Price₹51678.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4667
- Product description(±)-Mevalonolactone ~97% (titration)
- Packaging5G
- Price₹37887.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM4667
- Product description(±)-Mevalonolactone ~97% (titration)
- Packaging1G
- Price₹13098.25
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D0587 | DL-Mevalonolactone min. 98.0 % | 100MG | ₹3200 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | M4667 | (±)-Mevalonolactone ~97% (titration) | 10G | ₹51678.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M4667 | (±)-Mevalonolactone ~97% (titration) | 5G | ₹37887.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M4667 | (±)-Mevalonolactone ~97% (titration) | 1G | ₹13098.25 | 2022-06-14 | Buy |
Properties
Melting point :28 °C(lit.)
Boiling point :145-150 °C5 mm Hg(lit.)
alpha :-1.0～+1.0°(20℃/D)(c=5, C2H5OH)
Density :1.1066 (rough estimate)
refractive index :n20/D 1.473(lit.)
Flash point :>230 °F
storage temp. :-20°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate, Methanol (Slightly)
form :Oil
pka :13.57±0.20(Predicted)
color :Pale Yellow to Dark Brown
Merck :14,6163
BRN :80960
Stability :Hygroscopic
InChIKey :JYVXNLLUYHCIIH-UHFFFAOYSA-N
CAS DataBase Reference :674-26-0(CAS DataBase Reference)
NIST Chemistry Reference :Dl-mevalonic acid lactone(674-26-0)
Boiling point :145-150 °C5 mm Hg(lit.)
alpha :-1.0～+1.0°(20℃/D)(c=5, C2H5OH)
Density :1.1066 (rough estimate)
refractive index :n
Flash point :>230 °F
storage temp. :-20°C
solubility :Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate, Methanol (Slightly)
form :Oil
pka :13.57±0.20(Predicted)
color :Pale Yellow to Dark Brown
Merck :14,6163
BRN :80960
Stability :Hygroscopic
InChIKey :JYVXNLLUYHCIIH-UHFFFAOYSA-N
CAS DataBase Reference :674-26-0(CAS DataBase Reference)
NIST Chemistry Reference :Dl-mevalonic acid lactone(674-26-0)
Safety Information
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Description
DL-Mevalonolactone is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. It induces depolarization and swelling, decreases NADPH content and aconitase (ACO) activity, and increases malondialdehyde (MDA) production in calcium-loaded rat brain mitochondria. DL-Mevalonolactone reverses decreases in glucose uptake induced by simvastatin (Item Nos. 10010344 | 10010345) in L6 myotubes. Tissue levels and urinary excretion of DL-mevalonolactone are increased in patients with mevalonic aciduria, a disorder characterized by a deficiency in mevalonic kinase activity.Related product price
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