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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Esters >Methyl ester compound >Diphosgene

Diphosgene

Diphosgene Structure
  • ₹6559.95 - ₹51400
  • Product name: Diphosgene
  • CAS: 503-38-8
  • MF: C2Cl4O2
  • MW: 197.83
  • EINECS:207-965-9
  • MDL Number:MFCD00015553
  • Synonyms:Carbonochloridicacid,trichloromethylester ;Disphosgene;Trichloromethylchloroformate=Diphosgene;Trichloromethylchloroformate,98%;DIPHOSGENE (conmtrolled chemical);Trichloromethylchloroformate, 97% + 22764 Deposit Required;(Trichloromethoxy)formic acid chloride;Chloridocarbonic acid trichloromethyl ester
4 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10ML
  • 25ML
  • 50ML
  • 100ML
  • ManufacturerSigma-Aldrich(India)
  • Product number23261
  • Product descriptionTrichloromethyl chloroformate ≥97.0% (GC)
  • Packaging10ML
  • Price₹6559.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number23261
  • Product descriptionTrichloromethyl chloroformate ≥97.0% (GC)
  • Packaging50ML
  • Price₹16951.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.18154
  • Product descriptionTrichloromethyl chloroformate for synthesis
  • Packaging25ML
  • Price₹17480.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number8.18154
  • Product descriptionTrichloromethyl chloroformate for synthesis
  • Packaging100ML
  • Price₹51400
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 23261 Trichloromethyl chloroformate ≥97.0% (GC) 10ML ₹6559.95 2022-06-14 Buy
Sigma-Aldrich(India) 23261 Trichloromethyl chloroformate ≥97.0% (GC) 50ML ₹16951.95 2022-06-14 Buy
Sigma-Aldrich(India) 8.18154 Trichloromethyl chloroformate for synthesis 25ML ₹17480.01 2022-06-14 Buy
Sigma-Aldrich(India) 8.18154 Trichloromethyl chloroformate for synthesis 100ML ₹51400 2022-06-14 Buy

Properties

Melting point :-57 °C
Boiling point :20 °C10 mm Hg(lit.)
Density :1.64
refractive index :n20/D 1.458
Flash point :>110°C
storage temp. :2-8°C
solubility :Chloroform (Soluble), Ethyl Acetate (Sparingly)
form :Liquid
color :Clear colorless
Water Solubility :may decompose
Sensitive :Moisture Sensitive
Merck :14,3334
BRN :970225
Stability :Hygroscopic, Moisture Sensitive
CAS DataBase Reference :503-38-8(CAS DataBase Reference)
NIST Chemistry Reference :Trichloromethyl chloroformate(503-38-8)
EPA Substance Registry System :Carbonochloridic acid, trichloromethyl ester (503-38-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Trichloromethyl chloroformate is used as a reagent in the synthesis of organic compounds. It serves as a source of phosgene used in some laboratory preparations. Also, it is used as a reactant for the synthesis of cyclic carbamimidates, N-alkenyl and cycloalkyl carbamates and prostate-specific membrane antigen-targeted anticancer prodrugs. In addition, it is involved in the preparation of an erythromycin A derivatives and antibody-drug conjugates. It is utilized in the conversion of amines, carboxylic acids, formamides in to isocyanates, acid chlorides and isocyanides respectively.

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