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ChemicalBook > Product Catalogue >API >Digestive system drugs >Gastrointestinal motility drugs >Domperidone

Domperidone

Domperidone Structure
  • ₹6386.75 - ₹69864.55
  • Product name: Domperidone
  • CAS: 57808-66-9
  • MF: C22H24ClN5O2
  • MW: 425.91
  • EINECS:260-968-7
  • MDL Number:MFCD00069256
  • Synonyms:midazol-1-yl)propyl)-4-piperidinyl)- ;Domperidone,Motilium;5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one;DoMperidone-d6;DoMperidone Sustained Release Pellets;Domperidone, >=99%;DataBase Reference;DOMPERIDONE - 10% W/W PELLETS
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • 200MG
  • 500MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4125
  • Product descriptionDomperidone
  • Packaging200MG
  • Price₹13100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4125
  • Product descriptionDomperidone
  • Packaging1G
  • Price₹17400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD122
  • Product descriptionDomperidone powder, ≥98% (HPLC)
  • Packaging25MG
  • Price₹6386.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD122
  • Product descriptionDomperidone powder, ≥98% (HPLC)
  • Packaging100MG
  • Price₹17428.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD122
  • Product descriptionDomperidone powder, ≥98% (HPLC)
  • Packaging500MG
  • Price₹69864.55
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4125 Domperidone 200MG ₹13100 2022-05-26 Buy
TCI Chemicals (India) D4125 Domperidone 1G ₹17400 2022-05-26 Buy
Sigma-Aldrich(India) D122 Domperidone powder, ≥98% (HPLC) 25MG ₹6386.75 2022-06-14 Buy
Sigma-Aldrich(India) D122 Domperidone powder, ≥98% (HPLC) 100MG ₹17428.25 2022-06-14 Buy
Sigma-Aldrich(India) D122 Domperidone powder, ≥98% (HPLC) 500MG ₹69864.55 2022-06-14 Buy

Properties

Melting point :240-244°C
Density :1.2904 (rough estimate)
refractive index :1.5400 (estimate)
storage temp. :Store at RT
solubility :DMSO: >10 mg/mL
pka :pKa 7.90 (Uncertain)
form :solid
color :white
Water Solubility :Slightly soluble in water.
Merck :14,3418
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :FGXWKSZFVQUSTL-UHFFFAOYSA-N
CAS DataBase Reference :57808-66-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Domperidone is a dopamine receptor antagonist that does not readily cross the blood-brain barrier. It demonstrates a potent affinity for the rat D2 receptor with a Ki value of 0.3 nM (IC50 = 13.6 nM) and is also reported to inhibit the rat D3 receptor with an IC50 value of 2.68 nM. Both antiemetic and upper gastrointestinal tract prokinetic activities of domperidone have been evaluated in clinical trials.

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