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ESTETROL

ESTETROL Structure
  • ₹22819.1 - ₹88256.23
  • Product name: ESTETROL
  • CAS: 15183-37-6
  • MF: C18H24O4
  • MW: 304.38
  • EINECS:
  • MDL Number:MFCD00198996
  • Synonyms:1,3,5(10)-ESTRATRIEN-3,15-ALPHA, 16-ALPHA, 17-BETA-TETROL;15-ALPHA-HYDROXYESTRIOL;E 4;ESTETROL;(15a,16a,17)-Estra-1,3,5(10)-triene-3,15,16,17-tetrol;15a-Hydroxyestriol;3,15a,16a,17-Tetrahydroxyestra-1,3,5(10)-triene;Estra-1,3,5(10)-triene-3,15a,16a,17-tetrol
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1523
  • Product descriptionEstetrol ≥98% (HPLC)
  • Packaging5MG
  • Price₹22819.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1523
  • Product descriptionEstetrol ≥98% (HPLC)
  • Packaging25MG
  • Price₹88256.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1523 Estetrol ≥98% (HPLC) 5MG ₹22819.1 2022-06-14 Buy
Sigma-Aldrich(India) SML1523 Estetrol ≥98% (HPLC) 25MG ₹88256.23 2022-06-14 Buy

Properties

Melting point :233-236°C
Boiling point :491.9±45.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :10.22±0.70(Predicted)
color :white to beige
optical activity :[α]/D +125 to +135, c = 1 in ethanol

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol and estriol during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium). In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.

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