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ChemicalBook > Product Catalogue >API >Anesthetic Agents >Skeletal muscle relaxants >Edrophonium chloride

Edrophonium chloride

Edrophonium chloride Structure
  • ₹0
  • Product name: Edrophonium chloride
  • CAS: 116-38-1
  • MF: C10H16ClNO
  • MW: 201.69
  • EINECS:204-138-4
  • MDL Number:MFCD00055064
  • Synonyms:ETHYL[M-HYDROXYPHENYL]-DIMETHYLAMMONIUM CHLORIDE;EDROPHONIUM CHLORIDE;N-Ethyl-3-hydroxy-N,N-diMethyl-benzenaMiniuM Chloride;Reversol;Tensilon Chloride;antirex ;dimethylethyl(m-hydroxyphenyl)-ammoniuchloride ;ethyl(m-hydroxyphenyl)dimethyl-ammoniuchloride
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Properties

Melting point :162-163 °C (decomp)
Density :1.0787 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Inert atmosphere,Room Temperature
solubility :Very soluble in water, freely soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
form :A crystalline solid
color :White to light yellow
InChIKey :BXKDSDJJOVIHMX-UHFFFAOYSA-N
CAS DataBase Reference :116-38-1(CAS DataBase Reference)

Safety Information

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Description

Edrophonium (chloride) is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site. It has been shown to inhibit AChE activity in human red blood cells, purified calf forebrain, and purified octopus brain with Ki values of 0.2, 0.2, and 0.4 μM, respectively. Edrophonium is often used as part of a battery of pharmacological tests to confirm a diagnosis of the autoimmune neuromuscular junction disorder, myasthenia gravis.

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