β-Elemonic Acid
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- Product name: β-Elemonic Acid
- CAS: 28282-25-9
- MF: C30H46O3
- MW: 454.68
- EINECS:300-005-5
- MDL Number:MFCD32661885
- Synonyms:BETA-ELEMONIC ACID;Elemadienonic acid;Beta-EleMonic;3-OXOTIRUCALLA-8,24-DIEN-21-OIC ACID;β-deMonic acid;(13α,14β,17α,20S)-3-Oxolanosta-8,24-dien-21-oic acid;B-ELEMONIC ACID;(13α,14β,17α,20S)-3-Oxo-5α-lanosta-8,24-dien-21-oic acid
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Properties
Melting point :224-225°C
Boiling point :565.2±50.0 °C(Predicted)
Density :1.07
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :4.65±0.10(Predicted)
color :White to off-white
Boiling point :565.2±50.0 °C(Predicted)
Density :1.07
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :4.65±0.10(Predicted)
color :White to off-white
Safety Information
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Description
β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.More related product prices
17019-92-0 ALPHA-BOSWELLIC ACID 67416-61-9 89913-60-0 Incensol BETA-BOSWELLIC ACID CITRONELLIC ACIDRelated product price
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Suppliers and manufacturers
Chengdu Greenpure Biopharma CO.,Ltd
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Xi'an Kono chem co., Ltd.,
Shaanxi Pioneer Biotech Co., Ltd .
Neostar United (Changzhou) Industrial Co., Ltd.
Hubei Ipure Biology Co., Ltd
ANHUI WITOP BIOTECH CO., LTD
Hebei Guanlang Biotechnology Co., Ltd.