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ChemicalBook > Product Catalogue >Analytical Chemistry >Analysis reagents >Ion chromatography reagents >β-Elemonic Acid

β-Elemonic Acid

β-Elemonic Acid Structure
  • ₹0
  • Product name: β-Elemonic Acid
  • CAS: 28282-25-9
  • MF: C30H46O3
  • MW: 454.68
  • EINECS:300-005-5
  • MDL Number:MFCD32661885
  • Synonyms:BETA-ELEMONIC ACID;Elemadienonic acid;Beta-EleMonic;3-OXOTIRUCALLA-8,24-DIEN-21-OIC ACID;β-deMonic acid;(13α,14β,17α,20S)-3-Oxolanosta-8,24-dien-21-oic acid;B-ELEMONIC ACID;(13α,14β,17α,20S)-3-Oxo-5α-lanosta-8,24-dien-21-oic acid
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Properties

Melting point :224-225°C
Boiling point :565.2±50.0 °C(Predicted)
Density :1.07
storage temp. :2-8°C
solubility :DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :4.65±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro.

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