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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Antiamoebic and anti-trichomoniasis drugs >Emetine dihydrochloride

Emetine dihydrochloride

Emetine dihydrochloride Structure
  • ₹9396.1
  • Product name: Emetine dihydrochloride
  • CAS: 316-42-7
  • MF: C29H42Cl2N2O4
  • MW: 553.56
  • EINECS:206-259-8
  • MDL Number:MFCD00135589
  • Synonyms:6’,7’,10,11-tetramethoxy-emetadihydrochloride ;ai3-50600 ;emetine,dihydrochloride1/ ;l-emetinedihydrochloride ;nsc-33669 ;purum ;6',7',10,11-TETRAMETHOXYEMETAN, 2HCL;6',7',10,11-TETRAMETHOXYMETHANE 2HCL
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberE2375
  • Product descriptionEmetine dihydrochloride
  • Packaging50MG
  • Price₹9396.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E2375 Emetine dihydrochloride 50MG ₹9396.1 2022-06-14 Buy

Properties

Melting point :240-250 °C (dec., dry matter)(lit.)
alpha :D +11° (c = 1) to D +21° (c = 8)
storage temp. :2-8°C
solubility :DMSO:55.36(Max Conc. mg/mL);100.0(Max Conc. mM)
form :White solid with a faint yellow cast
Water Solubility :Soluble to 100 mM in water
Merck :14,3559
Stability :Stable. Combustible. Incompatible with strong oxidizing agents. Light and heat sensitive.
EPA Substance Registry System :Emetine, dihydrochloride (316-42-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

As the principal alkaloid of ipecac, Emetine dihydrochloride is derived from Uragoga ipecacuanha ground roots, which is used in the treatment of amebiasis. It can  also be used as an emetic to induce vomiting.
Emetine dihydrochloride functions by inhibiting ribosome movement along mRNA, which results in irreversibly blocking protein synthesis in eukaryotic cells  instead of prokaryotic cells. Besides, it has been proved that it can induce hypotension through blocking adrenoreceptors.

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