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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Emtricitabine

Emtricitabine

Emtricitabine Structure
  • ₹2900 - ₹8000
  • Product name: Emtricitabine
  • CAS: 143491-57-0
  • MF: C8H10FN3O3S
  • MW: 247.25
  • EINECS:604-363-1
  • MDL Number:MFCD00870151
  • Synonyms:Emtricitabine (200 mg);4-aMino-5-fluoro-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyriMidin-2-one;EMtricitabine (EMtriva);4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)-b-23Dideoxy-5-fluoro-3thiacytidine, 524W91, BW-52491, Coviracil,;Entricitabine;2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl-;2'-deoxy-5-fluoro-3'-thiacytidine;4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)--2’,3’-Dideoxy-5-fluoro-3’-thiacytidine, 524W91, BW-52491, Coviracil
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 25MG
  • 250MG
  • ManufacturerTCI Chemicals (India)
  • Product numberE1007
  • Product descriptionEmtricitabine
  • Packaging25MG
  • Price₹2900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE1007
  • Product descriptionEmtricitabine
  • Packaging250MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E1007 Emtricitabine 25MG ₹2900 2022-05-26 Buy
TCI Chemicals (India) E1007 Emtricitabine 250MG ₹8000 2022-05-26 Buy

Properties

Melting point :136-140°C
alpha :D25 -133.60° (c = 0.23 in MeOH)
Boiling point :443.3±55.0 °C(Predicted)
Density :1.82±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Chloroform (Slightly)
form :Solid
pka :13.83±0.10(Predicted)
color :White to Pale Yellow
λmax :280nm(H2O)(lit.)
Merck :14,3565
BCS Class :1
InChIKey :XQSPYNMVSIKCOC-NTSWFWBYSA-N
CAS DataBase Reference :143491-57-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Emtricitabine is a cytidine analog with an unnatural β-L structural configuration that inhibits reverse transcriptase, preventing replication of HIV-1 (EC50 = 10-20 nM) and hepatitis B (EC50 = 10-40 nM). It is activated through multistep intracellular phosphorylation by various cellular kinases. Emtricitabine, when used alone or in combination therapies, has been shown to reduce viral load and to induce immunological clearance via T cells.

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Suppliers and manufacturers

KARPSCHEM LABORATORIES Varanous Labs Pvt Ltd Styrax Pharma Pvt Ltd Aurobindo Pharma Limited Lupin Ltd Cipla Ltd Hetero Drugs Limited Macleods Pharmaceuticals Limited KRS Pharmaceuticals Pvt. Ltd. HRV Global Life Sciences