Eprosartan mesylate
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- ₹8000 - ₹32929.65
- Product name: Eprosartan mesylate
- CAS: 144143-96-4
- MF: C24H28N2O7S2
- MW: 520.62
- EINECS:658-063-0
- MDL Number:MFCD08141807
- Synonyms:Eprosartan mesylate, >=99%;(E)-4-((2-butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-enyl)-1H-imidazol-1-yl)methyl)benzoic acid;Eprosartan Myslate;4-[[2-butyl-5-(2-carboxy-3-thiophen-2-yl-prop-1-enyl)-imidazol-1-yl]methyl]benzoic acid mesylate;EPROSARTAN MESYLATE;4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylMethyl)eth-1-en-1-yl]-1H-iMidazol-1-yl}Methyl)benzoic acid;(E)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid Methanesulfonate;(αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid MonoMethanesulfonate
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberE1161
- Product descriptionEprosartan Mesylate
- Packaging200MG
- Price₹8000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberE1161
- Product descriptionEprosartan Mesylate
- Packaging1G
- Price₹19500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE2535
- Product descriptionEprosartan mesylate ≥98% (HPLC)
- Packaging50MG
- Price₹32929.65
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE2535
- Product descriptionEprosartan mesylate ≥98% (HPLC)
- Packaging10MG
- Price₹8746.6
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | E1161 | Eprosartan Mesylate | 200MG | ₹8000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | E1161 | Eprosartan Mesylate | 1G | ₹19500 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | E2535 | Eprosartan mesylate ≥98% (HPLC) | 50MG | ₹32929.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E2535 | Eprosartan mesylate ≥98% (HPLC) | 10MG | ₹8746.6 | 2022-06-14 | Buy |
Properties
Melting point :248-250°
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >10mg/mL
form :powder
color :white to off-white
Merck :14,3635
InChIKey :DJSLTDBPKHORNY-XMMWENQYSA-N
CAS DataBase Reference :144143-96-4(CAS DataBase Reference)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >10mg/mL
form :powder
color :white to off-white
Merck :14,3635
InChIKey :DJSLTDBPKHORNY-XMMWENQYSA-N
CAS DataBase Reference :144143-96-4(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Angiotensin II, as part of the renin-angiotensin-aldosterone system, facilitates a sympathetic nervous system response mediated by the angiotensin II type 1 (AT1) receptor, causing vasoconstriction and subsequent increase in blood pressure. It potentiates noradrenaline release from sympathetic nerve terminals at the presynaptic level as well as amplifies the α-adrenoceptor-mediated vasoconstrictor response to endogenous noradrenaline. Angiotensin II receptor blockers (ARBs) are a major class of therapeutics designed to lower blood pressure and to provide cardiovascular protection. Eprosartan (mesylate) is a competitive AT1 receptor antagonist with IC50 values ranging from 1.4 – 3.9 nM and an elimination half-life of five to seven hours. Eprosartan is structurally distinct from other noncompetitive ARBs in that it does not contain a biphenyl, tetrazole moiety and blocks angiotensin II receptors on both sympathetic nerve terminals and blood vessels.Related product price
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