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FMoc-Val-Cit-PAB-PNP

FMoc-Val-Cit-PAB-PNP Structure
  • ₹5700 - ₹18400
  • Product name: FMoc-Val-Cit-PAB-PNP
  • CAS: 863971-53-3
  • MF: C40H42N6O10
  • MW: 766.8
  • EINECS:
  • MDL Number:MFCD22200278
  • Synonyms:FMoc-Val-Cit-PAB-PNP;{4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]pentanamido]phenyl}methyl 4-nitrophenyl carbonate;Moc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PAB-PNP, >95%;L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-;FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE);4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate;(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 100MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberF1114
  • Product descriptionFmoc-Val-Cit-PAB-PNP
  • Packaging500MG
  • Price₹18400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF1114
  • Product descriptionFmoc-Val-Cit-PAB-PNP
  • Packaging100MG
  • Price₹5700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F1114 Fmoc-Val-Cit-PAB-PNP 500MG ₹18400 2022-05-26 Buy
TCI Chemicals (India) F1114 Fmoc-Val-Cit-PAB-PNP 100MG ₹5700 2022-05-26 Buy

Properties

Melting point :189 °C(dec.)
Boiling point :1024.0±65.0 °C(Predicted)
Density :1.335±0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
form :powder to crystal
pka :10.63±0.46(Predicted)
color :White to Light yellow
Sequence :Fmoc-Val-Cit-PAB-PNP

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Fmoc-Val-Cit-PAB-PNP is a a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. PNP group is a good leaving group when reacting with amine bearing payload.

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