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Fmoc-N-amido-PEG1-acid

Fmoc-N-amido-PEG1-acid Structure
  • ₹0
  • Product name: Fmoc-N-amido-PEG1-acid
  • CAS: 1654740-73-4
  • MF: C20H21NO5
  • MW: 355.38
  • EINECS:
  • MDL Number:MFCD16294357
  • Synonyms:Fmoc-N-amido-PEG1-acid;Fmoc-PEG1-propionic acid;Fmoc-AEP;3-[2-(Fmoc-amino)ethoxy]propanoic acid;6-(Fmoc-amino)-4-oxahexanoic Acid;Fmoc-PEG1- CH2CH2COOH;Fmoc-NH-PEG1-C2-acid;Propanoic acid, 3-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethoxy]-
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :589.9±40.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :4.29±0.10(Predicted)
form :Solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Fmoc-N-amido-PEG1-acid is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.