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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Antigout Drugs >Febuxostat

Febuxostat

Febuxostat Structure
  • ₹9600 - ₹20448.43
  • Product name: Febuxostat
  • CAS: 144060-53-7
  • MF: C16H16N2O3S
  • MW: 316.37
  • EINECS:682-158-6
  • MDL Number:MFCD00871598
  • Synonyms:Febuxostat (Uloric);Febuxostat (TEI-6720);Febuxostat Tablets;FEBUXOSTAT API;Febuxostat (This product is unavailable in the U.S.);Febuxostat Tabletshehe;Febuxostat 2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid;Febuxostat, >=99%
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberF0847
  • Product descriptionFebuxostat
  • Packaging1G
  • Price₹9600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0847
  • Product descriptionFebuxostat
  • Packaging5G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1285
  • Product descriptionFebuxostat 98.5-102.0% (HPLC)
  • Packaging1G
  • Price₹20448.43
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0847 Febuxostat 1G ₹9600 2022-05-26 Buy
TCI Chemicals (India) F0847 Febuxostat 5G ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) SML1285 Febuxostat 98.5-102.0% (HPLC) 1G ₹20448.43 2022-06-14 Buy

Properties

Melting point :238-239°(dec.)
Boiling point :536.6±60.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :2.48±0.10(Predicted)
color :White to Off-White
Merck :14,3948
InChI :InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
InChIKey :BQSJTQLCZDPROO-UHFFFAOYSA-N
SMILES :S1C(C(O)=O)=C(C)N=C1C1=CC=C(OCC(C)C)C(C#N)=C1
CAS DataBase Reference :144060-53-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. It is 10-30 times more potent than the hypoxanthine analog allopurinol (Kis = 0.7 nM versus 0.7 μM, respectively). In various clinical trials, 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

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