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ChemicalBook > Product Catalogue >API >Specialty drugs >Antidote >Flumazenil

Flumazenil

Flumazenil Structure
  • ₹4800 - ₹109083.53
  • Product name: Flumazenil
  • CAS: 78755-81-4
  • MF: C15H14FN3O3
  • MW: 303.29
  • EINECS:616-650-9
  • MDL Number:MFCD00242764
  • Synonyms:FluMenazil;Ro 15-1788/000;Ro 1722;Ro 41-8157;FluMazenil API;FluMazenil(Ro 15-1788);ethyl 12-fluoro-8-Methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate;Ethyl 8-fluoro-5-methyl-5,6-dihydro-6-oxo-4H-imidazo(1,5-a)(1,4)benzodiazepine-3-carboxylate
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberF0958
  • Product descriptionFlumazenil min. 99.0 %
  • Packaging25MG
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0958
  • Product descriptionFlumazenil min. 99.0 %
  • Packaging100MG
  • Price₹15000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF6300
  • Product descriptionFlumazenil >99% (HPLC), solid
  • Packaging25MG
  • Price₹31587.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2702
  • Product descriptionFlumazenil certified reference material, pharmaceutical secondary standard
  • Packaging500MG
  • Price₹61951.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF6300
  • Product descriptionFlumazenil >99% (HPLC), solid
  • Packaging100MG
  • Price₹109083.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0958 Flumazenil min. 99.0 % 25MG ₹4800 2022-05-26 Buy
TCI Chemicals (India) F0958 Flumazenil min. 99.0 % 100MG ₹15000 2022-05-26 Buy
Sigma-Aldrich(India) F6300 Flumazenil >99% (HPLC), solid 25MG ₹31587.35 2022-06-14 Buy
Sigma-Aldrich(India) PHR2702 Flumazenil certified reference material, pharmaceutical secondary standard 500MG ₹61951.48 2022-06-14 Buy
Sigma-Aldrich(India) F6300 Flumazenil >99% (HPLC), solid 100MG ₹109083.53 2022-06-14 Buy

Properties

Melting point :201-203°C
Boiling point :528.0±50.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO to 25mM
pka :0.86±0.20(Predicted)
form :solid
color :white
Water Solubility :128 mg/L
Merck :14,4135
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :78755-81-4(CAS DataBase Reference)
NIST Chemistry Reference :Flumazenil(78755-81-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403 Store in a well-ventilated place.

Description

Flumazenil is an imidazobenzodiazepine derivative that competitively inhibits benzodiazepine binding to GABAA receptors with an IC50 value of 2 nM. Flumazenil is non-selective for α1, α2, α3, or α5 subunit-containing GABAA receptors and antagonizes the actions of benzodiazepines on the central nervous system without producing the behavioral or neurological effects typical of the benzodiazepines. Flumazenil has been used to reverse sedation induced by benzodiazepine drugs and has been found to be effective in the treatment of benzodiazepine overdose or withdrawal.

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Suppliers and manufacturers

CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Indogulf Group SynZeal Research Pvt Ltd Pharma Affiliates SPB Pharma Chiemimpex Vyshno Bio Sciences Oceanic Pharmachem Pvt. Ltd.