Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Antineoplastic agents >Hormonal antineoplastic drugs >Flutamide

Flutamide

Flutamide Structure
  • ₹4990.33 - ₹23479.43
  • Product name: Flutamide
  • CAS: 13311-84-7
  • MF: C11H11F3N2O3
  • MW: 276.21
  • EINECS:236-341-9
  • MDL Number:MFCD00072009
  • Synonyms:TIMTEC-BB SBB006930;N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE;2-METHYL-N-(4-NITRO-3-[TRIFLUOROMETHYL]PHENYL)PROPANAMIDE;FLUTAMIDE;AURORA KA-860;2-Methyl-N-[4-nitro-3-(trifluoromethyl)-phenyl]-propionamide;Flutamide USP25
5 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberF0663
  • Product descriptionFlutamide min. 98.0 %
  • Packaging5G
  • Price₹8400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0663
  • Product descriptionFlutamide min. 98.0 %
  • Packaging25G
  • Price₹15400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF9397
  • Product descriptionFlutamide
  • Packaging1G
  • Price₹4990.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF9397
  • Product descriptionFlutamide
  • Packaging5G
  • Price₹16291.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number94495
  • Product descriptionFlutamide certified reference material, TraceCERT?
  • Packaging50MG
  • Price₹23479.43
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0663 Flutamide min. 98.0 % 5G ₹8400 2022-05-26 Buy
TCI Chemicals (India) F0663 Flutamide min. 98.0 % 25G ₹15400 2022-05-26 Buy
Sigma-Aldrich(India) F9397 Flutamide 1G ₹4990.33 2022-06-14 Buy
Sigma-Aldrich(India) F9397 Flutamide 5G ₹16291.63 2022-06-14 Buy
Sigma-Aldrich(India) 94495 Flutamide certified reference material, TraceCERT? 50MG ₹23479.43 2022-06-14 Buy

Properties

Melting point :112 °C
Boiling point :400.3±45.0 °C(Predicted)
Density :1.3649 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent).
pka :13.12±0.70(Predicted)
form :Solid
color :Pale Yellow to Light Yellow
Merck :14,4208
InChI :InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChIKey :MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES :C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)(=O)C(C)C
CAS DataBase Reference :13311-84-7(CAS DataBase Reference)
EPA Substance Registry System :Flutamide (13311-84-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR), preventing androgens such as testosterone and its active metabolite dihydrotestosterone from binding to ARs in the prostate gland. This process inhibits androgen-dependent DNA and protein synthesis in the tumor cell. Therefore, it can prevent androgens from stimulating the growth of prostate cancer cells. Moreover, it can also be used for the treatment of hyperandrogenism in women. It is quite effective in alleviating symptoms such as acne, seborrhea, hirsutism and androgenetic alopecia. Finally, it is also useful as a component in the transgender hormone therapy.

Related product price