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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Hormonal antineoplastic drugs >Formestane

Formestane

Formestane Structure
  • ₹16713.8 - ₹50560.5
  • Product name: Formestane
  • CAS: 566-48-3
  • MF: C19H26O3
  • MW: 302.41
  • EINECS:625-331-3
  • MDL Number:MFCD00057814
  • Synonyms:4-hydroxy-androst-4-ene-17-dione ;4-hydroxy-delta(sub4)-androstenedione ;4-HYDROXYANDROST-4-ENE-3,17-DIONE;4-HYDROXYANDROSTENEDIONE;4-HYDROXY-4-ANDROSTENE-3,17-DIONE;4-ANDROSTEN-4-OL-3,17-DIONE;4-OHA;CGP-32349
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 100μG
  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberF2552
  • Product descriptionFormestane solid
  • Packaging1G
  • Price₹16713.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB4500606
  • Product descriptionAnti-Cytochrome P450 19A1 antibody produced in rabbit affinity isolated antibody
  • Packaging100μG
  • Price₹50560.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) F2552 Formestane solid 1G ₹16713.8 2022-06-14 Buy
Sigma-Aldrich(India) SAB4500606 Anti-Cytochrome P450 19A1 antibody produced in rabbit affinity isolated antibody 100μG ₹50560.5 2022-06-14 Buy

Properties

Melting point :199-202°C
alpha :D20 +181° (c = 7.7 in chloroform)
Boiling point :383.44°C (rough estimate)
Density :1.1189 (rough estimate)
refractive index :1.4200 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :solid
pka :9.31±0.60(Predicted)
color :White to Off-White
InChI :InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1
InChIKey :OSVMTWJCGUFAOD-KZQROQTASA-N
SMILES :C1(=O)C(O)=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2
CAS DataBase Reference :566-48-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

4-hydroxy Androstenedione (4-HAD) is a steroidal inhibitor of aromatase (also known as cytochrome P450 19A1; Ki = 27 nM). As aromatase catalyzes the conversion of androgens to estrogens, aromatase inhibitors, including 4-HAD, are used against hormone-sensitive breast cancer in menopausal women. They are also abused in combination with anabolic steroids in racehorses and athletes. This product is intended for forensic and research applications.

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