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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Hormonal antineoplastic drugs >Fulvestrant

Fulvestrant

Fulvestrant Structure
  • ₹17742.18 - ₹20520
  • Product name: Fulvestrant
  • CAS: 129453-61-8
  • MF: C32H47F5O3S
  • MW: 606.77
  • EINECS:642-998-6
  • MDL Number:MFCD00903953
  • Synonyms:zd182780 ;zm182780 ;(1S,9R,10R,11S,14S,15S)-15-Methyl-9-{9-[(R)-(4,4,5,5,5-pentafluoropentane)sulfinyl]nonyl}tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol;Fulvestrant Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7 ,17 )-;Fulvestrant (Faslodex);ZD 9238;Fulvestrant(ICI 182,780);(717b)- 7-[9-[4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberI4409
  • Product descriptionFulvestrant >98% (HPLC)
  • Packaging25MG
  • Price₹17742.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.31042
  • Product descriptionEstrogen Receptor Antagonist, ICI 182,780 - CAS 129453-61-8 - Calbiochem A cell-permeable estrogen antagonist. More effective than tamoxifen in reducing estrogen receptors in breast tumor cells.
  • Packaging10MG
  • Price₹20520
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) I4409 Fulvestrant >98% (HPLC) 25MG ₹17742.18 2022-06-14 Buy
Sigma-Aldrich(India) 5.31042 Estrogen Receptor Antagonist, ICI 182,780 - CAS 129453-61-8 - Calbiochem A cell-permeable estrogen antagonist. More effective than tamoxifen in reducing estrogen receptors in breast tumor cells. 10MG ₹20520 2022-06-14 Buy

Properties

Melting point :104-106°C
Boiling point :674.8±55.0 °C(Predicted)
Density :1.201±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
form :powder
pka :10.27±0.70(Predicted)
color :White
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :VWUXBMIQPBEWFH-WCCTWKNTSA-N
SMILES :[C@@]12([H])[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)CC3C=C(O)C=CC=3[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,2,32,36,38,41,r|
CAS DataBase Reference :129453-61-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

ICI 182,780 is a high affinity estrogen receptor antagonist (IC50 = 0.29 nM), devoid of any partial agonism in vitro and ICI 182,780 is also a high affinity agonist at the membrane estrogen receptor, GPR30.

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