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ChemicalBook > Product Catalogue >API >Urinary System Drugs >Diuretics Drugs >Furosemide

Furosemide

Furosemide Structure
  • ₹3560 - ₹50769.25
  • Product name: Furosemide
  • CAS: 54-31-9
  • MF: C12H11ClN2O5S
  • MW: 330.74
  • EINECS:200-203-6
  • MDL Number:MFCD00010549
  • Synonyms:4-CHLORO-N-FURFURYL-5-SULFAMOYLANTHRANILIC ACID;5-(AMINOSULPHONYL)-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;5-[AMINOSULFONYL]-4-CHLORO-2-[(2-FURANYLMETHYL)AMINO]BENZOIC ACID;LABOTEST-BB LT00244801;FUROSEMID;FUROSEMIDE;FRUSEMIDE;2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid
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Brand

  • Sigma-Aldrich(India)
  • SRL

Package

  • 400μL
  • 1G
  • 1ML
  • 5G
  • 10G
  • 25G
  • 5Gms
  • 25Gms
  • ManufacturerSigma-Aldrich(India)
  • Product numberF-005
  • Product descriptionFurosemide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹4189.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF4381
  • Product descriptionFurosemide
  • Packaging1G
  • Price₹5715.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1057
  • Product descriptionFurosemide Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9493.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberF4381
  • Product descriptionFurosemide
  • Packaging5G
  • Price₹27019.2
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberF4381
  • Product descriptionFurosemide
  • Packaging10G
  • Price₹31457.45
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberF4381
  • Product descriptionFurosemide
  • Packaging25G
  • Price₹50769.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB1306550
  • Product descriptionANTI-TM173(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution
  • Packaging400μL
  • Price₹47796.6
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberSAB1306152
  • Product descriptionANTI-TM173(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution
  • Packaging400μL
  • Price₹47796.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number18641
  • Product descriptionFurosemide (Frusemide), 98.5%
  • Packaging5Gms
  • Price₹3560
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number18641
  • Product descriptionFurosemide (Frusemide), 98.5%
  • Packaging25Gms
  • Price₹9930
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) F-005 Furosemide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹4189.5 2022-06-14 Buy
Sigma-Aldrich(India) F4381 Furosemide 1G ₹5715.6 2022-06-14 Buy
Sigma-Aldrich(India) PHR1057 Furosemide Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9493.53 2022-06-14 Buy
Sigma-Aldrich(India) F4381 Furosemide 5G ₹27019.2 2022-06-14 Buy
Sigma-Aldrich(India) F4381 Furosemide 10G ₹31457.45 2022-06-14 Buy
Sigma-Aldrich(India) F4381 Furosemide 25G ₹50769.25 2022-06-14 Buy
Sigma-Aldrich(India) SAB1306550 ANTI-TM173(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 400μL ₹47796.6 2022-06-14 Buy
Sigma-Aldrich(India) SAB1306152 ANTI-TM173(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 400μL ₹47796.6 2022-06-14 Buy
SRL 18641 Furosemide (Frusemide), 98.5% 5Gms ₹3560 2022-05-26 Buy
SRL 18641 Furosemide (Frusemide), 98.5% 25Gms ₹9930 2022-05-26 Buy

Properties

Melting point :220 °C (dec.) (lit.)
Boiling point :582.1±60.0 °C(Predicted)
Density :1.606
refractive index :1.6580 (estimate)
Flash point :11 °C
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
form :powder
pka :pKa 3.8 (Uncertain)
color :White to Off-White
Water Solubility :Soluble in acetone, DMF or methanol. Slightly soluble in water
Merck :14,4309
BCS Class :2 (CLogP), 4 (LogP)
Stability :Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :ZZUFCTLCJUWOSV-UHFFFAOYSA-N
CAS DataBase Reference :54-31-9(CAS DataBase Reference)
IARC :3 (Vol. 50) 1990
EPA Substance Registry System :Furosemide (54-31-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Furosemide is an inhibitor of the Na+/K+/2Cl- (NKCC) cotransporters, NKCC1 and NKCC2 (Ki = ~10 μM for each). It is commonly used as a loop diuretic, blocking NKCC2 action on the apical membrane of the thick ascending limb of Henle epithelial cells. Furosemide also acts as an antagonist of GABAA receptors and as an inhibitor of carbonic anhydrase and organic anion transporter 1.

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