GOSSYPOL
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- ₹20751.53 - ₹41568
- Product name: GOSSYPOL
- CAS: 303-45-7
- MF: C30H30O8
- MW: 518.55
- EINECS:636-899-7
- MDL Number:MFCD00017352
- Synonyms:Gossypol from cotton seeds,2,2′-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene);Thespesin;GOSSYPOL;NSC 624336;NSC 56817;1,1',6,6',7,7'-HEXAHYDROXY-3,3'-DIMETHYL-5,5'-BIS(1-METHYLETHYL)-[2,2'-BINAPHTHALENE]-8,8'-DICARBOXALDEHYDE;2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPHTHALENE];2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPTHALENE]
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 100MG
- 250MG
- ManufacturerSigma-Aldrich(India)
- Product numberG8761
- Product description(±)-Gossypol from cotton seeds ≥95% (HPLC)
- Packaging100MG
- Price₹20751.53
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG8761
- Product description(±)-Gossypol from cotton seeds ≥95% (HPLC)
- Packaging250MG
- Price₹41568
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | G8761 | (±)-Gossypol from cotton seeds ≥95% (HPLC) | 100MG | ₹20751.53 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G8761 | (±)-Gossypol from cotton seeds ≥95% (HPLC) | 250MG | ₹41568 | 2022-06-14 | Buy |
Properties
Melting point :181-183 C
Boiling point :522.63°C (rough estimate)
Density :1.1912 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :≥25.95 mg/mL in DMSO; insoluble in H2O; ≥2.1 mg/mL in EtOH
form :Off-white to yellow solid.
pka :7.15±0.50(Predicted)
color :Light yellow to yellow
Water Solubility :Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.
InChIKey :QBKSWRVVCFFDOT-UHFFFAOYSA-N
LogP :5.419 (est)
CAS DataBase Reference :303-45-7
EPA Substance Registry System :[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)- (303-45-7)
Boiling point :522.63°C (rough estimate)
Density :1.1912 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :≥25.95 mg/mL in DMSO; insoluble in H2O; ≥2.1 mg/mL in EtOH
form :Off-white to yellow solid.
pka :7.15±0.50(Predicted)
color :Light yellow to yellow
Water Solubility :Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.
InChIKey :QBKSWRVVCFFDOT-UHFFFAOYSA-N
LogP :5.419 (est)
CAS DataBase Reference :303-45-7
EPA Substance Registry System :[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)- (303-45-7)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | ||||||||||||||
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Description
Gossypol is a racemic mixture of natural polyphenols isolated from parts of the cotton plant (genus Gossypium). It causes infertility in a variety of cotton pests and spermatogenesis arrest in humans. Gossypol also has antimalarial properties, preventing the growth of P. falciparum at low micromolar concentrations. It inhibits aldose reductase (Ki = 0.5 μM). Gossypol also acts as an anticancer agent, inhibiting cell growth in various cancer cell lines, in part by blocking the anti-apoptotic functions of Bcl-2 and Bcl-xL, again at low micromolar concentrations.More related product prices
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