Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >GUANETHIDINE SULFATE

GUANETHIDINE SULFATE

GUANETHIDINE SULFATE Structure
  • ₹0
  • Product name: GUANETHIDINE SULFATE
  • CAS: 645-43-2
  • MF: C10H24N4O4S
  • MW: 296.39
  • EINECS:211-442-0
  • MDL Number:MFCD00035403
  • Synonyms:GUANETHIDINE MONOSULFATE;GUANETHIDINE MONOSULFATE (1:1);GUANETHIDINE SULFATE;(2-(hexahydro-1(2h)-azocinyl)ethyl)guanidinehydrogensulfate ;(2-(hexahydro-1(2h)-azocinyl)ethyl)-guanidinsulfate(1:1) ;2-(octahydro-1-azocinyl)ethylguanidinesulphate ;n-(2-guanidinoethyl)heptamethyleniminesulfate ;Guanethidine Sulphae
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :276-281 °C
storage temp. :2-8°C
solubility :Freely soluble in water, practically insoluble in ethanol (96 per cent)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChIKey :YUFWAVFNITUSHI-UHFFFAOYSA-N
CAS DataBase Reference :645-43-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Guanethidine is an antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter. Once guanethidine has entered the nerve, it becomes concentrated in synaptic vesicles, depleting endogenous norepinephrine, and thus, reducing the release of norepinephrine in response to action potentials. Guanethidine’s actions are restricted to peripheral nerve terminals because its basic guanidine group does not allow passage through the blood brain barrier. Its use has been explored in the relief of chronic pain caused by complex regional pain syndrome.

Related product price