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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >Ginkgolic acid

Ginkgolic acid

Ginkgolic acid Structure
  • ₹18830 - ₹32431.7
  • Product name: Ginkgolic acid
  • CAS: 22910-60-7
  • MF: C22H34O3
  • MW: 346.5
  • EINECS:200-683-7
  • MDL Number:MFCD03093717
  • Synonyms:C-17:1;GINKGOLIC ACID;ROMANICARDIC ACID;Ginkgolic;C10794;6-[(8Z)-Pentadecenyl]-salicylic acid, Ginkgolic acid I;2-Hydroxy-6-[(8Z)-8-pentadecenyl]benzoic acid;2-Hydroxy-6-[(Z)-8-pentadecenyl]benzoic acid
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number5.08197
  • Product descriptionInSolution Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem A 25 mM (2 mg/231 μl) sterile-filtered solution of Ginkgolic Acid (15:1) in DMSO.
  • Packaging2MG
  • Price₹18830
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number345887
  • Product descriptionGinkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem A cell-permeable anacardic acid analog that inhibits protein SUMO .
  • Packaging5MG
  • Price₹23839.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number75741
  • Product descriptionGinkgolic acid C15:1 analytical standard
  • Packaging5MG
  • Price₹32431.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 5.08197 InSolution Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem A 25 mM (2 mg/231 μl) sterile-filtered solution of Ginkgolic Acid (15:1) in DMSO. 2MG ₹18830 2022-06-14 Buy
Sigma-Aldrich(India) 345887 Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem A cell-permeable anacardic acid analog that inhibits protein SUMO . 5MG ₹23839.99 2022-06-14 Buy
Sigma-Aldrich(India) 75741 Ginkgolic acid C15:1 analytical standard 5MG ₹32431.7 2022-06-14 Buy

Properties

Melting point :45~48℃
storage temp. :2-8°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :White solid
Boiling point :221-223 °C(Press: 4 Torr)
Density :0.9148 g/cm3
pka :3.08±0.30(Predicted)
color :White to Off-White
InChIKey :YXHVCZZLWZYHSA-FPLPWBNLSA-N
LogP :9.269 (est)
CAS DataBase Reference :22910-60-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.

Description

Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts. Ginkgolic acid C15:1 is a 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position. It inhibits SUMOylation in vitro (IC50 = 3 μM) and in cells without affecting protein ubiquitination. Ginkgolic acid C15:1 directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate. Ginkgolic acid C15:1 also suppresses the development of pancreatic cancer xenografts in mice.

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