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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Epigenetics >Histone Acetyltransferase inhibitors >6-pentadecylsalicylic acid

6-pentadecylsalicylic acid

6-pentadecylsalicylic acid Structure
  • ₹15469.99 - ₹63488.63
  • Product name: 6-pentadecylsalicylic acid
  • CAS: 16611-84-0
  • MF: C22H36O3
  • MW: 348.52
  • EINECS:
  • MDL Number:MFCD07368254
  • Synonyms:NSC 333857;NSC 623096;(15:0)-Anacardic acid;Ginkgolic Acid 15:0 〔Anacardic Acid 15:0〕;Hodrogenated anacardic acid;PENTADECYLSALICYLICACID;6-Pentadecyl-2-hydroxybenzoic acid;Cyclogallipharic acid
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA7236
  • Product descriptionAnacardic acid
  • Packaging25MG
  • Price₹63488.63
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number05506
  • Product description(15:0)-Anacardic acid analytical standard
  • Packaging10MG
  • Price₹31132.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA7236
  • Product descriptionAnacardic acid
  • Packaging5MG
  • Price₹15891.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number172050
  • Product descriptionAnacardic Acid - CAS 16611-84-0 - Calbiochem The Anacardic Acid, also referenced under CAS 16611-84-0, modulates the biological activity of Anacardic. This small molecule/inhibitor is primarily u
  • Packaging10MG
  • Price₹15469.99
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A7236 Anacardic acid 25MG ₹63488.63 2022-06-14 Buy
Sigma-Aldrich(India) 05506 (15:0)-Anacardic acid analytical standard 10MG ₹31132.7 2022-06-14 Buy
Sigma-Aldrich(India) A7236 Anacardic acid 5MG ₹15891.1 2022-06-14 Buy
Sigma-Aldrich(India) 172050 Anacardic Acid - CAS 16611-84-0 - Calbiochem The Anacardic Acid, also referenced under CAS 16611-84-0, modulates the biological activity of Anacardic. This small molecule/inhibitor is primarily u 10MG ₹15469.99 2022-06-14 Buy

Properties

Melting point :90-91℃
Boiling point :474.8±33.0 °C(Predicted)
Density :1.002
storage temp. :-20°C
solubility :DMSO: ≥20mg/mL
form :White solid
pka :3.08±0.30(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :ADFWQBGTDJIESE-UHFFFAOYSA-N
LogP :9.960 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (PCAF) with IC50 values of 8.5 and 5 μM, respectively. At 25 μmol/L, anacardic acid suppresses NF-κB activation, inhibits IκB-α phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

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