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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >HYPERFORIN

HYPERFORIN

HYPERFORIN Structure
  • ₹23421.3
  • Product name: HYPERFORIN
  • CAS: 11079-53-1
  • MF: C35H52O4
  • MW: 536.78
  • EINECS:601-000-9
  • MDL Number:MFCD01861497
  • Synonyms:Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-;methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-;4-HYDROXY-6R-METHYL-1R,3,7S-TRIS(3-METHYL-2-BUTENYL)-5S-(2-METHYL-1-OXOPROPYL)-6R-(4-METHYL-3-PENTENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE;HYPERFORIN;(1R,5S)-4-Hydroxy-6-methyl-1,3,7β-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6α-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione;HYPERFORIN MIX(P);Hyperforin (solution in Ethanol);Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-
1 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 250μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberH5160
  • Product descriptionHyperforin ≥85% (HPLC)
  • Packaging250μG
  • Price₹23421.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) H5160 Hyperforin ≥85% (HPLC) 250μG ₹23421.3 2022-06-14 Buy

Properties

Melting point :79-80℃
alpha :D18 +41° (in ethanol)
Boiling point :616.8±55.0 °C(Predicted)
Density :1.010±0.06 g/cm3 (20 ºC 760 Torr)
Flash point :9℃
storage temp. :-20°C
form :solution
pka :4.8 (50% aq ethanol)
CAS DataBase Reference :11079-53-1

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

St. John’s wort is a widely consumed herbal preparation which has been claimed to have a number of medicinal properties. It contains a number of known lipid signalling mediators, including chlorogenic acid, hypericin, hyperforin, and I3,II8-biapigenin. Hyperforin exhibits two activities which may alter the action of other concurrent medications. It inhibits the activity of several CYP450 enzymes, with CYP2D6 being the most sensitive with an IC50 of about 10 μg/ml. Hyperforin is also a ligand for the steroid X receptor (SXR). Since one activity of this receptor is the induction of CYP450 expression, the exact nature of hyperforin’s drug-drug interactions must be evaluated on a case-by-case basis. However, these interactions certainly complicate its use as a human therapeutic.

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