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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >Harpagoside

Harpagoside

Harpagoside Structure
  • ₹14202.4
  • Product name: Harpagoside
  • CAS: 19210-12-9
  • MF: C24H30O11
  • MW: 494.49
  • EINECS:242-881-6
  • MDL Number:MFCD00017415
  • Synonyms:HARPAGOSIDE;Harpagosid;[1S-[1alpha,4aalpha,5alpha,7alpha(E),7aalpha]]-1,4a,5,6,7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[(allyl-1-oxo-3-phenyl)oxy]cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside;[(1S,4aS,5R,7S,7aS)-4a,5-Dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate;HARPAGOSIDE WITH HPLC;7,7a-hexahydro-4a,5-dihydroxy-7-methyl-7-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]cyclopenta[c]pyran-1-yl;β-D-Glucopyranoside, (1S,4aS,5R,7S,7aS)-1,4a,5,6;8-O-E CINNAMOYL HARPAGIDE
Price1 Properties Safety Information Description
1 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product number68527
  • Product descriptionHarpagoside analytical standard
  • Packaging10MG
  • Price₹14202.4
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 68527 Harpagoside analytical standard 10MG ₹14202.4 2022-06-14 Buy

Properties

Melting point :120°C (dec.)
Boiling point :720.7±60.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :11.70±0.70(Predicted)
form :Solid
color :White to Light Yellow
Stability :Hygroscopic
InChIKey :KVRQGMOSZKPBNS-FMHLWDFHSA-N
LogP :-1.591 (est)
CAS DataBase Reference :19210-12-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Harpagoside is an anti-inflammatory small molecule natural product originally isolated from the Harpagophytum procumbens (Devil’s Claw) root, but can be isolated from other plants such as Crophularia ningpoensis Hemsl (Figwort). Treatment of HepG2 cells with Harpagoside demonstrated suppression of NF-κB nuclear translocation and degradation of IκB-α, blocking NF-κB activation. Multiple anti-inflammatory cellular effects were correlated with this blockade, as Harpagoside was observed to inhibit the expression of inflammation-mediating enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and to reduce lipopolysaccharide-induced mRNA levels. The suppression of NF-κB activation is indicated as the mechanism beneath the anti-inflammatory effects of Harpagoside.

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Suppliers and manufacturers

Sinoway Industrial co., ltd.
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₹0.00 /1Kg/Bag
Harpagoside CAS:19210-12-9
Hebei Kingfiner Technology Development Co.Ltd
Harpagoside
₹0.00 /1kg
Harpagoside CAS:19210-12-9
Shaanxi Haibo Biotechnology Co., Ltd
Harpagoside
₹0.00 /25kg
Harpagoside CAS:19210-12-9
Henan Fengda Chemical Co., Ltd
Harpagoside
₹0.10 /1000KG
Harpagoside CAS:19210-12-9
BINBO BIOLOGICAL CO.,LTD
Harpagoside
₹0.00 /1kg
Harpagoside CAS:19210-12-9
A.J Chemicals CLEARSYNTH LABS LTD. Pharma Affiliates Pharmaffiliates Analytics and Synthetics P. Ltd
Chengdu Greenpure Biopharma CO.,Ltd