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ChemicalBook > Product Catalogue >API >Urinary System Drugs >Diuretics Drugs >Hydrochlorothiazide

Hydrochlorothiazide

Hydrochlorothiazide Structure
  • ₹2966.05 - ₹18456.63
  • Product name: Hydrochlorothiazide
  • CAS: 58-93-5
  • MF: C7H8ClN3O4S2
  • MW: 297.74
  • EINECS:200-403-3
  • MDL Number:MFCD00051765
  • Synonyms:2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-, 1,1-dioxide;3,4-Dihydro-6-chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide;6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide ;6-Chloro-3,4-dihydro-7-sulphamoyl-1,2,4-ben-zoth-iadi-azine1,1-dioxcide ;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine ;6-Chloro-7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide;200-403-3;6-chloro-7-sulfamoyl-3,4-dihydro-2h-1,2,4-benzothiadiazine-1,1-dioxide
Price7 Properties Safety Information Description
7 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • 1ML
  • 5G
  • 25G
  • 100G
  • ManufacturerSigma-Aldrich(India)
  • Product numberH2910
  • Product descriptionHydrochlorothiazide meets USP testing specifications
  • Packaging5G
  • Price₹2966.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH-001
  • Product descriptionHydrochlorothiazide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹4189.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH4759
  • Product descriptionHydrochlorothiazide crystalline
  • Packaging5G
  • Price₹4524.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH4759
  • Product descriptionHydrochlorothiazide crystalline
  • Packaging25G
  • Price₹5715.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1032
  • Product descriptionHydrochlorothiazide Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9590.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH2910
  • Product descriptionHydrochlorothiazide meets USP testing specifications
  • Packaging25G
  • Price₹12004.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH4759
  • Product descriptionHydrochlorothiazide crystalline
  • Packaging100G
  • Price₹18456.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) H2910 Hydrochlorothiazide meets USP testing specifications 5G ₹2966.05 2022-06-14 Buy
Sigma-Aldrich(India) H-001 Hydrochlorothiazide solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹4189.5 2022-06-14 Buy
Sigma-Aldrich(India) H4759 Hydrochlorothiazide crystalline 5G ₹4524.85 2022-06-14 Buy
Sigma-Aldrich(India) H4759 Hydrochlorothiazide crystalline 25G ₹5715.6 2022-06-14 Buy
Sigma-Aldrich(India) PHR1032 Hydrochlorothiazide Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9590.95 2022-06-14 Buy
Sigma-Aldrich(India) H2910 Hydrochlorothiazide meets USP testing specifications 25G ₹12004.93 2022-06-14 Buy
Sigma-Aldrich(India) H4759 Hydrochlorothiazide crystalline 100G ₹18456.63 2022-06-14 Buy

Properties

Melting point :273 °C
Boiling point :577.0±60.0 °C(Predicted)
Density :1.6761 (rough estimate)
refractive index :1.6100 (estimate)
Flash point :9℃
storage temp. :2-8°C
solubility :Very slightly soluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides
pka :7.9, 9.2(at 25℃)
form :solid
color :White to Off-White
Odor :wh. or pract. wh. cryst. powd., odorless
Water Solubility :722mg/L(25 ºC)
λmax :318nm(H2O)(lit.)
Merck :14,4781
BRN :625101
BCS Class :3,4
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :JZUFKLXOESDKRF-UHFFFAOYSA-N
LogP :-0.070
CAS DataBase Reference :58-93-5(CAS DataBase Reference)
IARC :2B (Vol. 50, 108) 2016
NIST Chemistry Reference :6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide(58-93-5)
EPA Substance Registry System :Hydrochlorothiazide (58-93-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Hydrochlorothiazide is a kind of thiazide diuretic drugs with moderate diuretic effect. It exert is diuretic effect through acting on the medullary ascending limb cortical segment, inhibiting the active re-absorption of Cl-and passive absorption of Na+ at this site. In addition, the product also has a hypotensive effect and anti-diuretic effect. It is suitable for treating a variety of edema, particularly for cardiogenic edema. It can also be used as antihypertensive agents, for treatment light, medium hypertension. It also has certain efficacy in treating diabetes insipidus, and idiopathic hypercalciuria. Commonly used thiazide diuretics include hydrochlorothiazide, chlorthalidone, indapamide and the like.

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