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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Immunosuppressants >Hydroxyurea

Hydroxyurea

Hydroxyurea Structure
  • ₹2370.68 - ₹124303.48
  • Product name: Hydroxyurea
  • CAS: 127-07-1
  • MF: CH4N2O2
  • MW: 76.05
  • EINECS:204-821-7
  • MDL Number:MFCD00007943
  • Synonyms:Carbamohydroximic acid;Hidroxicarbamida;Hydurea;N-(aminocarbonyl)hydroxylamine;wr 83799;hydrixycarbamide ;HYDROXYUREA;Urea,N-hydroxy-
14 prices
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Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)
  • ottokemi

Package

  • 300MG
  • 1gm
  • 1G
  • 5G
  • 5gm
  • 10G
  • 25G
  • 25gm
  • 100G
  • 250G
  • ManufacturerSigma-Aldrich(India)
  • Product numberV900323
  • Product descriptionHydroxyurea Vetec?, reagent grade, ≥98%
  • Packaging100G
  • Price₹2370.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH8627
  • Product descriptionHydroxyurea 98%, powder
  • Packaging1G
  • Price₹4124.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberV900323
  • Product descriptionHydroxyurea Vetec?, reagent grade, ≥98%
  • Packaging250G
  • Price₹5488.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number400046
  • Product descriptionHydroxyurea - CAS 127-07-1 - Calbiochem Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase.
  • Packaging5G
  • Price₹10550.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH8627
  • Product descriptionHydroxyurea 98%, powder
  • Packaging5G
  • Price₹11918.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2629
  • Product descriptionHydroxyurea Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging300MG
  • Price₹14722
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberH8627
  • Product descriptionHydroxyurea 98%, powder
  • Packaging10G
  • Price₹20751.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH8627
  • Product descriptionHydroxyurea 98%, powder
  • Packaging25G
  • Price₹45140.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH8627
  • Product descriptionHydroxyurea 98%, powder
  • Packaging100G
  • Price₹124303.48
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0310
  • Product descriptionHydroxyurea
  • Packaging5G
  • Price₹4200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0310
  • Product descriptionHydroxyurea
  • Packaging25G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number H 1719
  • Product descriptionHydroxyurea 98%
  • Packaging1gm
  • Price₹2403
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number H 1719
  • Product descriptionHydroxyurea 98%
  • Packaging5gm
  • Price₹3789
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number H 1719
  • Product descriptionHydroxyurea 98%
  • Packaging25gm
  • Price₹9729
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) V900323 Hydroxyurea Vetec?, reagent grade, ≥98% 100G ₹2370.68 2022-06-14 Buy
Sigma-Aldrich(India) H8627 Hydroxyurea 98%, powder 1G ₹4124.33 2022-06-14 Buy
Sigma-Aldrich(India) V900323 Hydroxyurea Vetec?, reagent grade, ≥98% 250G ₹5488.28 2022-06-14 Buy
Sigma-Aldrich(India) 400046 Hydroxyurea - CAS 127-07-1 - Calbiochem Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase. 5G ₹10550.01 2022-06-14 Buy
Sigma-Aldrich(India) H8627 Hydroxyurea 98%, powder 5G ₹11918.33 2022-06-14 Buy
Sigma-Aldrich(India) PHR2629 Hydroxyurea Pharmaceutical Secondary Standard; Certified Reference Material 300MG ₹14722 2022-06-14 Buy
Sigma-Aldrich(India) H8627 Hydroxyurea 98%, powder 10G ₹20751.53 2022-06-14 Buy
Sigma-Aldrich(India) H8627 Hydroxyurea 98%, powder 25G ₹45140.25 2022-06-14 Buy
Sigma-Aldrich(India) H8627 Hydroxyurea 98%, powder 100G ₹124303.48 2022-06-14 Buy
TCI Chemicals (India) H0310 Hydroxyurea 5G ₹4200 2022-05-26 Buy
TCI Chemicals (India) H0310 Hydroxyurea 25G ₹10800 2022-05-26 Buy
ottokemi H 1719 Hydroxyurea 98% 1gm ₹2403 2022-05-26 Buy
ottokemi H 1719 Hydroxyurea 98% 5gm ₹3789 2022-05-26 Buy
ottokemi H 1719 Hydroxyurea 98% 25gm ₹9729 2022-05-26 Buy

Properties

Melting point :135-140 °C
Boiling point :136.04°C (rough estimate)
Density :1.457±0.06 g/cm3(Predicted)
refractive index :1.4840 (estimate)
storage temp. :2-8°C
solubility :H2O: 50 mg/mL
form :powder
pka :10.56±0.23(Predicted)
color :white
Odor :odorless or almost odorless
Water Solubility :soluble
Merck :14,4848
BRN :1741548
Stability :Stable for 2 years as supplied from date of purchase. Solutions in water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :127-07-1(CAS DataBase Reference)
IARC :3 (Vol. 76) 2000
EPA Substance Registry System :Hydroxyurea (127-07-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

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