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Ingenol

Ingenol Structure
  • ₹2600 - ₹9800
  • Product name: Ingenol
  • CAS: 30220-46-3
  • MF: C20H28O5
  • MW: 348.43
  • EINECS:
  • MDL Number:MFCD27980538
  • Synonyms:1A,2,5,5A,6,9,10,10A OCTAHYDRO-5,5A,6-TRIHYDROXY4(HYDROXYMETHYL)1,1,7,9-TETRAMETHYL1H-2,8 AMETHANOCYCLOPENTA[A]CYCLOPROPA[E]CYCLODECEN-11 ONE;1 ALPHA,2,5,5 ALPHA,6,9,10,10 ALPHA-OCTAHYDRO-5,5 ALPHA,6-TRIHYDROXY-4-HYDROXYMETHYL-1,1,7,9-RETRAMETHYL-1H-2,8 ALPHA-M;INGENOL;INGENOL \ ACTIVATES PROTEIN KINASE C;(1ar,2s,5r,5ar,6s,8as,9r,10ar)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1h-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one;INGENOL,HIGHPURITY;1alpha,2,5,5alpha,6,9,10,10alpha-Octahydro-5,5alpha,6-trihydroxy-4-hydroxymethyl-1,1,7,9,-retramethyl-1H-2,8alpha-m;(1aR,2S,8aS)-1aα,2,5,5a,6,9,10,10aα-Octahydro-5β,5aβ,6β-trihydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-2,8aα-methano-1H-cyclopenta[a]cyclopropa[e]cyclodecene-11-one
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 10MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberI1112
  • Product descriptionIngenol
  • Packaging10MG
  • Price₹2600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI1112
  • Product descriptionIngenol
  • Packaging50MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I1112 Ingenol 10MG ₹2600 2022-05-26 Buy
TCI Chemicals (India) I1112 Ingenol 50MG ₹9800 2022-05-26 Buy

Properties

Melting point :153 °C
Boiling point :523.8±50.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble
form :film
pka :12.06±0.70(Predicted)
color :colorless

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ingenol is a diterpenoid related to phorbol, derived from the milkweed plant E. peplus. It is a protein kinase C activator that displays a Ki value of 30 μM and an ED50 value of 27 μM in vitro. Most ingenol esters are tumor-promoting. However, ingenol mebutate possesses anti-tumor activity when used topically for actinic keratosis.

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