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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Tinib Antineoplastic drugs >Imatinib mesylate

Imatinib mesylate

Imatinib mesylate Structure
  • ₹4306.8 - ₹15740
  • Product name: Imatinib mesylate
  • CAS: 220127-57-1
  • MF: C30H35N7O4S
  • MW: 589.71
  • EINECS:606-892-3
  • MDL Number:MFCD04307699
  • Synonyms:4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]phenyl]benzamide;Imatinib mesylate / 4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;Gleevec (Imatinib);IMatinib Mesylate(STI-571);Gleevec, Glivec, CGP-57148B, STI-571;4-[(4-Methyl-1-piperazinyl)Methyl]-N-[4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]phenyl]benzaMide Methanesulfonate;IMATINIB METHANESULFONATE;CGP-57148B
6 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0936
  • Product descriptionImatinib Mesylate
  • Packaging100MG
  • Price₹7900
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0936
  • Product descriptionImatinib Mesylate
  • Packaging1G
  • Price₹13900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1027
  • Product descriptionImatinib mesylate ≥98% (HPLC)
  • Packaging10MG
  • Price₹4306.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberCDS022105
  • Product descriptionImatinib mesylate
  • Packaging100MG
  • Price₹7393.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1027
  • Product descriptionImatinib mesylate ≥98% (HPLC)
  • Packaging100MG
  • Price₹14652
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.04595
  • Product descriptionBcr-abl Inhibitor IV, Imatinib - CAS 220127-57-1 - Calbiochem
  • Packaging50MG
  • Price₹15740
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0936 Imatinib Mesylate 100MG ₹7900 2022-05-26 Buy
TCI Chemicals (India) I0936 Imatinib Mesylate 1G ₹13900 2022-05-26 Buy
Sigma-Aldrich(India) SML1027 Imatinib mesylate ≥98% (HPLC) 10MG ₹4306.8 2022-06-14 Buy
Sigma-Aldrich(India) CDS022105 Imatinib mesylate 100MG ₹7393.48 2022-06-14 Buy
Sigma-Aldrich(India) SML1027 Imatinib mesylate ≥98% (HPLC) 100MG ₹14652 2022-06-14 Buy
Sigma-Aldrich(India) 5.04595 Bcr-abl Inhibitor IV, Imatinib - CAS 220127-57-1 - Calbiochem 50MG ₹15740 2022-06-14 Buy

Properties

Melting point :214-224°C
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :White solid
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 3 months.
InChIKey :YLMAHDNUQAMNNX-UHFFFAOYSA-N
SMILES :C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)(=O)C1=CC=C(CN2CCN(C)CC2)C=C1.CS(O)(=O)=O
CAS DataBase Reference :220127-57-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Imatinib (mesylate) is a first generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GIST), and other cancers. It selectively targets certain tyrosine kinases, including c-ABL, platelet-derived growth factor receptor, and KIT. In CML, imatinib (mesylate) inhibits the oncoprotein BCR-ABL, the product of the Philadelphia chromosome gene fusion.

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