Indiplon
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- Product name: Indiplon
- CAS: 325715-02-4
- MF: C20H16N4O2S
- MW: 376.43
- EINECS:
- MDL Number:MFCD09264193
- Synonyms:INDIPLON;Acetamide, N-methyl-N-(3-(3-(2-thienylcarbonyl)pyrazolo(1,5-A)pyrimidin-7-yl)phenyl)-;Nbi 34060;Unii-8bt63da42e;N-Methyl-N-[3-[3-[2-thienylcarbonyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide;AcetaMide,N-Methyl-N-[3-[3-(2-thienylcarbonyl)pyrazolo[1,5-a]pyr;N-Methyl-N-[3-[3-(thien-2-ylcarbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide;N-methyl-N-[3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]acetamide
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Properties
Melting point :>192oC (dec.)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka :-1.42±0.50(Predicted)
form :Solid
color :Light Yellow to Dark Yellow
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka :-1.42±0.50(Predicted)
form :Solid
color :Light Yellow to Dark Yellow
Safety Information
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Description
Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric modulator of the GABAA receptor, potentiating GABA-activated chloride currents in a dose-dependent and reversible manner. Indiplon is selective for α1 subunits (EC50 = 2.6 nM) as compared with α2, α3, or α5 (EC50 = 24, 60, and 77 nM). Through this action, indiplon has sedative and hypnotic effects that can improve sleep onset, maintenance, and duration.Related product price
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