Melting point :172-175 °C (lit.)
Boiling point :381.66°C (rough estimate)
Density :1.0597 (rough estimate)
refractive index :1.4800 (estimate)
storage temp. :-20°C
solubility :Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka :4.76±0.33(Predicted)
form :Fine Crystalline Powder
color :Yellow-orange to orange
Water Solubility :insoluble
λmax :354nm(EtOH)(lit.)
Merck :14,5228
Stability :Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
InChIKey :SHGAZHPCJJPHSC-YCNIQYBTSA-N
CAS DataBase Reference :4759-48-2(CAS DataBase Reference)
EPA Substance Registry System :Isotretinoin (4759-48-2)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362 H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
Precautionary statements:	P201 Obtain special instructions before use. P302+P352 IF ON SKIN: wash with plenty of soap and water. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P308+P313 IF exposed or concerned: Get medical advice/attention.