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KETOCONAZOLE INTERMEDIATE

KETOCONAZOLE INTERMEDIATE Structure
  • ₹0
  • Product name: KETOCONAZOLE INTERMEDIATE
  • CAS: 61397-58-8
  • MF: C14H14Cl2N2O3
  • MW: 329.18
  • EINECS:262-766-4
  • MDL Number:MFCD09033165
  • Synonyms:KETOCONAZOLE INTERMEDIATE;cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol ;[(R)-2-(2,4-DICHLORO-PHENYL)-2-IMIDAZOL-1-YLMETHYL-[1,3]DIOXOLAN-4-YL]-METHANOL;CIS-2-(2,4-DICHLOROPHENYL)-2- (1H-IMIDAZOL-1-YLMETHYL)-1,3;rel-2α*-(1H-Imidazole-1-ylmethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4α*-methanol;(2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-1,3-dioxolane-4-Methanol;1,3-Dioxolane-4-Methanol, 2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-, cis-;rac-Ketoconazole Hydroxymethyl Impurity
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Properties

Melting point :99-101 °C
Boiling point :529.1±50.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :14.20±0.10(Predicted)
color :White

Safety Information

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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).

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