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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Tyrosine derivatives >KN-62

KN-62

KN-62 Structure
  • ₹10367 - ₹70480
  • Product name: KN-62
  • CAS: 127191-97-3
  • MF: C38H35N5O6S2
  • MW: 721.84
  • EINECS:
  • MDL Number:MFCD00083180
  • Synonyms:1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-*N-M ETHYL-L-TYR;KN-62 97%;KN-62, 99+%;4-((2S)-2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenylisoquinolinesulfonicacid;1-(N,O-Bis-[5-isoquinolinesulfonyl]-N-methyl-L-tyrosyl)-4-phenylpiperazine, (S)-5-Isoquinolinesulfonic Acid 4-(2-[(5-Isoquinolinylsulfonyl)methylamino]- 3-oxo-3-[4-phenyl-1-piperazinyl]propyl)phenyl Ester,;5-Isoquinolinesulfonic acid, 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester;(s)-5-isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester;(1-(N,O-BIS-(5-ISOQUINOLINESULFONYL)-N-METHYL-L-TYROSYL)4-PHENYLPIPERAZINE) KN 62
5 prices
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Brand

  • Sigma-Aldrich(India)
  • ALFA India

Package

  • 1MG
  • 10mg
  • .5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberI2142
  • Product descriptionKN-62 ≥95%, powder
  • Packaging.5MG
  • Price₹13444.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number422706
  • Product descriptionKN-62 - CAS 127191-97-3 - Calbiochem A cell-permeable, reversible, and selective inhibitor of CaM kinase II (Ki = 900 nM for rat brain CaM kinase II) that binds directly to the calmodulin
  • Packaging1MG
  • Price₹19050
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberI2142
  • Product descriptionKN-62 ≥95%, powder
  • Packaging1MG
  • Price₹19907.18
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J62444-MA
  • Product descriptionKN-62
  • Packaging10mg
  • Price₹70480
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J62444-MCR
  • Product descriptionKN-62
  • Packaging1mg
  • Price₹10367
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) I2142 KN-62 ≥95%, powder .5MG ₹13444.65 2022-06-14 Buy
Sigma-Aldrich(India) 422706 KN-62 - CAS 127191-97-3 - Calbiochem A cell-permeable, reversible, and selective inhibitor of CaM kinase II (Ki = 900 nM for rat brain CaM kinase II) that binds directly to the calmodulin 1MG ₹19050 2022-06-14 Buy
Sigma-Aldrich(India) I2142 KN-62 ≥95%, powder 1MG ₹19907.18 2022-06-14 Buy
ALFA India ALF-J62444-MA KN-62 10mg ₹70480 2022-05-26 Buy
ALFA India ALF-J62444-MCR KN-62 1mg ₹10367 2022-05-26 Buy

Properties

Melting point :92-94°C
Boiling point :964.7±75.0 °C(Predicted)
Density :1.388
storage temp. :-20°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
form :solid
pka :4.07±0.13(Predicted)
color :white
CAS DataBase Reference :127191-97-3(CAS DataBase Reference)

Safety Information

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Description

KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII; IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 μM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).

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