L-KYNURENINE
- ₹3236.68 - ₹34250.3
- Product name: L-KYNURENINE
- CAS: 2922-83-0
- MF: C10H12N2O3
- MW: 208.21
- EINECS:
- MDL Number:MFCD00069912
- Synonyms:L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID;L-2-AMINO-4-[2-AMINOPHENYL]-4-OXOBUTANOIC ACID;L-KYNURENINE;L-kynurenine free base;β-Anthraniloyl-L-alanine;β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid;L-Kynurenine Hydrate;(S)-2-Amino-4-oxo-4-(2-aminophenyl)butanoic acid
6 prices
Selected condition:
Brand
- ALFA India
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 25MG
- 50mg
- 100MG
- 500MG
- 1G
- ManufacturerALFA India
- Product numberALF-J60199-MF
- Product descriptionL-Kynurenine
- Packaging50mg
- Price₹6381
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberK0016
- Product descriptionL-Kynurenine
- Packaging100MG
- Price₹5200
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberK8625
- Product descriptionL-Kynurenine ≥98% (HPLC)
- Packaging25MG
- Price₹3236.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberK8625
- Product descriptionL-Kynurenine ≥98% (HPLC)
- Packaging100MG
- Price₹8075.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberK8625
- Product descriptionL-Kynurenine ≥98% (HPLC)
- Packaging500MG
- Price₹16443.18
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberK8625
- Product descriptionL-Kynurenine ≥98% (HPLC)
- Packaging1G
- Price₹34250.3
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
ALFA India | ALF-J60199-MF | L-Kynurenine | 50mg | ₹6381 | 2022-05-26 | Buy |
TCI Chemicals (India) | K0016 | L-Kynurenine | 100MG | ₹5200 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | K8625 | L-Kynurenine ≥98% (HPLC) | 25MG | ₹3236.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | K8625 | L-Kynurenine ≥98% (HPLC) | 100MG | ₹8075.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | K8625 | L-Kynurenine ≥98% (HPLC) | 500MG | ₹16443.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | K8625 | L-Kynurenine ≥98% (HPLC) | 1G | ₹34250.3 | 2022-06-14 | Buy |
Properties
Melting point :219 °C
Boiling point :466.6±45.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
refractive index :-33 ° (C=0.4, H2O)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
form :crystalline
pka :2.21±0.23(Predicted)
color :light yellow
Merck :14,5328
Stability :Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference :2922-83-0(CAS DataBase Reference)
Boiling point :466.6±45.0 °C(Predicted)
Density :1.343±0.06 g/cm3(Predicted)
refractive index :-33 ° (C=0.4, H2O)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
form :crystalline
pka :2.21±0.23(Predicted)
color :light yellow
Merck :14,5328
Stability :Stable for 2 years as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
InChIKey :YGPSJZOEDVAXAB-QMMMGPOBSA-N
CAS DataBase Reference :2922-83-0(CAS DataBase Reference)
Safety Information
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Description
Kynurenine is a product of constitutive tryptophan catabolism via tryptophan-2,3-dioxygenase in the liver and human gliomas that is associated with the suppression of antitumor immune responses. At 100 μM, kynurenine inhibits allogeneic T-cell proliferation and increases malignant U87 glioma cell invasion into a collagen matrix. Kynurenine activates the aryl hydrocarbon receptor (AhR) target gene CYP1A1 with an EC50 value of 12.3 μM and binds to AhR with an apparent Kd value of ~4 μM. Kynurenine is ultimately metabolized to quinolinic acid, a potent neurotoxin that acts as an NMDA agonist and has been described to be involved in neurodegenerative processes in the brain.More related product prices
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