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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Apoptosis >IAP inhibitors >LCL-161

LCL-161

LCL-161 Structure
  • ₹0
  • Product name: LCL-161
  • CAS: 1005342-46-0
  • MF: C26H33FN4O3S
  • MW: 500.63
  • EINECS:
  • MDL Number:MFCD23160049
  • Synonyms:LCL-161;N-[(1S)-1-Cyclohexyl-2-{(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]-1-pyrrolidinyl}-2-oxoethyl]-N2-MethylalaninaMide;(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide;(S)-N-((S)-1-Cyclohexyl-2-((S)-2-(4-(4-fluorobenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl);N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-(2S)-propanamide;(2S)-N-[(1S)-1-Cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]-2-(methylamino)-propanamide LCL 161;LCL161, 98%, inhibitor of Apoptosis Protein (IAP) family of proteins;CS-987
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :713.7±60.0 °C(Predicted)
Density :1.245±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :14.25±0.46(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.

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