3-METHYLADENINE
|
- ₹13520 - ₹64960.83
- Product name: 3-METHYLADENINE
- CAS: 5142-23-4
- MF: C6H7N5
- MW: 149.15
- EINECS:225-908-6
- MDL Number:MFCD00010531
- Synonyms:3H-Purin-6-amine, 3-methyl-;3-methyl-3h-purin-6-amin ;3-Methyl-3H-purin-6-amine;3-methyl-adenin ;Adenine, 3-methyl-;3-METHYLADENINE;3-methyl-3H-adenine ;6-AMINO-3-METHYLPURINE
10 prices
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Brand
- Sigma-Aldrich
- TCI Chemicals (India)
- Sigma-Aldrich(India)
- ottokemi
Package
- 50MG
- 100MG
- 200MG
- 500MG
- 1gm
- 1G
- ManufacturerSigma-Aldrich
- Product number189490
- Product descriptionAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase.
- Packaging50MG
- Price₹13520
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich
- Product number189490
- Product descriptionAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase.
- Packaging100MG
- Price₹16920
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2518
- Product description3-Methyladenine
- Packaging200MG
- Price₹18900
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2518
- Product description3-Methyladenine
- Packaging1G
- Price₹19500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number189490
- Product descriptionAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase.
- Packaging50MG
- Price₹13520
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM9281
- Product description3-Methyladenine autophagy inhibitor
- Packaging100MG
- Price₹16454
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number189490
- Product descriptionAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase.
- Packaging100MG
- Price₹16920
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM9281
- Product description3-Methyladenine autophagy inhibitor
- Packaging500MG
- Price₹64960.83
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number M 4367
- Product description3-Methyladenine 98%
- Packaging100mg
- Price₹16029
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number M 4367
- Product description3-Methyladenine 98%
- Packaging1gm
- Price₹19404
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | 189490 | Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase. | 50MG | ₹13520 | 2022-06-14 | Buy |
| Sigma-Aldrich | 189490 | Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase. | 100MG | ₹16920 | 2022-06-14 | Buy |
| TCI Chemicals (India) | M2518 | 3-Methyladenine | 200MG | ₹18900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2518 | 3-Methyladenine | 1G | ₹19500 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 189490 | Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase. | 50MG | ₹13520 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9281 | 3-Methyladenine autophagy inhibitor | 100MG | ₹16454 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 189490 | Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker. Acts as an inhibitor of III PI3-Kinase. | 100MG | ₹16920 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9281 | 3-Methyladenine autophagy inhibitor | 500MG | ₹64960.83 | 2022-06-14 | Buy |
| ottokemi | M 4367 | 3-Methyladenine 98% | 100mg | ₹16029 | 2022-05-26 | Buy |
| ottokemi | M 4367 | 3-Methyladenine 98% | 1gm | ₹19404 | 2022-05-26 | Buy |
Properties
Melting point :~300 °C (dec.)(lit.)
Boiling point :240℃
Density :1.60
refractive index :1.8070 (estimate)
Flash point :99℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
pka :6.77±0.20(Predicted)
form :Powder
color :White
BRN :146087
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Boiling point :240℃
Density :1.60
refractive index :1.8070 (estimate)
Flash point :99℃
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
pka :6.77±0.20(Predicted)
form :Powder
color :White
BRN :146087
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms. mTOR, whose activation is controlled by phosphoinositide 3-kinase (PI3K), is a key regulator of autophagy. 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome. At 5 mM, 3-MA inhibits protein degradation in rat hepatocytes by 65%. 3-MA has been shown to block class I, class II, and class III PI3Ks, including some downstream targets, and to suppress the invasion of highly metastatic human fibrosarcoma HT1080 cells at 10 mM.More related product prices
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