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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Proteases >MMP inhibitors >3,4-Dichloro-N-(1-Methylbutyl)benza-Mide

3,4-Dichloro-N-(1-Methylbutyl)benza-Mide

3,4-Dichloro-N-(1-Methylbutyl)benza-Mide Structure
  • ₹11506.98 - ₹46590.8
  • Product name: 3,4-Dichloro-N-(1-Methylbutyl)benza-Mide
  • CAS: 7497-07-6
  • MF: C12H15Cl2NO
  • MW: 260.16
  • EINECS:804-136-9
  • MDL Number:MFCD02006898
  • Synonyms:3,4-Dichloro-N-(1-Methylbutyl)benza-Mide;NSC 405020;3,4-DICHLORO-N-(PENTAN-2-YL)BENZAMIDE;3,4-Dichloro-N-(1-methylbutyl)-benzamide NSC405020;NSC 405020 3,4-Dichloro-N-(1-methylbutyl)-benzamide;NSC 405020, >=98%;NSC 405020, 7497-07-6;NSC 405020;NSC-405020
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0518
  • Product descriptionNSC405020 ≥98% (HPLC)
  • Packaging5MG
  • Price₹11506.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0518
  • Product descriptionNSC405020 ≥98% (HPLC)
  • Packaging25MG
  • Price₹46590.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0518 NSC405020 ≥98% (HPLC) 5MG ₹11506.98 2022-06-14 Buy
Sigma-Aldrich(India) SML0518 NSC405020 ≥98% (HPLC) 25MG ₹46590.8 2022-06-14 Buy

Properties

Boiling point :353.7±32.0 °C(Predicted)
Density :1.182±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
pka :13.38±0.46(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NSC-405020 (7497-07-6) is a membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity?in vivo. (IC50?> 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2.? Suppresses bone erosion in a c-Fos-deficient mouse model.2?Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3

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