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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Metabolism >Dehydrogenase Inhibitor >PluriSln 1

PluriSln 1

PluriSln 1 Structure
  • ₹8800 - ₹18700
  • Product name: PluriSln 1
  • CAS: 91396-88-2
  • MF: C12H11N3O
  • MW: 213.24
  • EINECS:804-702-5
  • MDL Number:MFCD02344904
  • Synonyms:4-Pyridinecarboxylicacid, 2-phenylhydrazide;plurisln 1;NSC 14613;PluriSIn#1;N'-PHENYLISONICOTINOHYDRAZIDE;PluriSln 1, NSC 14613;NSC 14613, PluriSln 1;4-Pyridinecarboxylic acid 2-phenylhydrazide PluriSln 1 NSC 14613
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • TCI Chemicals (India)

Package

  • 20MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberI0975
  • Product descriptionPluriSIn 1
  • Packaging20MG
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0975
  • Product descriptionPluriSIn 1
  • Packaging100MG
  • Price₹18700
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0975 PluriSIn 1 20MG ₹8800 2022-05-26 Buy
TCI Chemicals (India) I0975 PluriSIn 1 100MG ₹18700 2022-05-26 Buy

Properties

Melting point :177-178℃
Boiling point :335.7±15.0 °C(Predicted)
Density :1.251±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble15mg/mL, clear
pka :10.69±0.23(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PluriSln 1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). PluriSln 1 can selectively induce ER stress, attenuate protein synthesis, and induce apoptosis in hPSCs (EC50 = 2 μM) while sparing progenitor and differentiated cells. Because PluriSln 1 can selectively eliminate undifferentiated hPSCs, it was developed as a strategy to prevent tumorigenic risk from residual undifferentiated cells used during stem cell therapy. In immunocompromised mice, PluriSln 1 has been shown to effectively prevent teratoma formation from undifferentiated hPSCs.

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Suppliers and manufacturers

career henan chemical co
PluriSln 1
₹5.00 /5KG
PluriSln 1 CAS:91396-88-2
Shaanxi Dideu Medichem Co. Ltd
1,4-Pyridinecarboxylicacid
₹0.00 /5mg
1,4-Pyridinecarboxylicacid CAS:91396-88-2
TCI Chemicals (India) Pvt. Ltd. CLEARSYNTH LABS LTD. A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
TargetMol Chemicals Inc.
Dideu Industries Group Limited