Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >protein tyrosine kinase >AZD-9291

AZD-9291

AZD-9291 Structure
  • ₹0
  • Product name: AZD-9291
  • CAS: 1421373-65-0
  • MF: C28H33N7O2
  • MW: 499.61
  • EINECS:629-848-5
  • MDL Number:MFCD27988062
  • Synonyms:N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide;Mereletinib mesylate(AZD9291);AZD9291 (free base);Osimertinib (AZD-9291);AZD9291, Osimertinib;AZD9291 Base;Osimertinib Base;AZD9291 10G
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>188oC (dec.)
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :12.68±0.70(Predicted)
form :Solid
color :Pale Yellow to Beige
CAS DataBase Reference :1421373-65-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AZD-9291 (Mesylate), also known as Osimertinib, belongs to a third-generation EGFR (epidermal growth factor receptor) inhibitor. It can be used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in case when the cancer cells carry specific mutations (such as T790M) in the epidermal growth factor receptor. It takes effect through directly binding to the certain mutant forms of EGFR (T790M, L858R, and exon 19 deletions) that are frequently found in NSCLC, further causing poor prognosis for late-stage disease. Since it spares wild type EGFR during therapy, it has only limited toxicity.

More related product prices

3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide 86604-78-6 Gefitinib Bortezomib Dacomitinib (PF299804) Poziotinib (HM781-36B) Neratinib Irbinitinib EGF816 OSI-420 AG 1478 HYDROCHLORIDE AZD 3759 Genistein XL-647 Olmutinib Afatinib (BIBW 2992) CO-1686 Erlotinib hydrochloride 871700-17-3

Related product price

Suppliers and manufacturers

Hebei Mojin Biotechnology Co., Ltd
AZD-9291
₹0.00 /25KG
AZD-9291 CAS:1421373-65-0
shandong perfect biotechnology co.ltd
Osimertinib (AZD9291)
₹0.00 /1g
Osimertinib (AZD9291) CAS:1421373-65-0
Henan Bao Enluo International TradeCo.，LTD
AZD-9291
₹50.00 /1kg
AZD-9291 CAS:1421373-65-0
SHANDONG BOYUAN PHARMACEUTICAL CO., LTD.
Osimertinib
₹0.00 /1kg
Osimertinib CAS:1421373-65-0
Henan Fengda Chemical Co., Ltd
AZD-9291
₹0.10 /1000KG
AZD-9291 CAS:1421373-65-0
Bulat Pharmaceutical Pvt Ltd Aspen Biopharma Labs Pvt Ltd CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd