Poziotinib (HM781-36B)
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- Product name: Poziotinib (HM781-36B)
- CAS: 1092364-38-9
- MF: C23H21Cl2FN4O3
- MW: 491.34
- EINECS:
- MDL Number:MFCD28044290
- Synonyms:1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one;UNII-OEI6OOU6IK;1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one;1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one;poziotinib(HM-78136B);NOV120101;1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib;HM781-36B)
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Properties
Melting point :187 - 190° C
Boiling point :629.7±55.0 °C(Predicted)
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka :5.35±0.30(Predicted)
form :Solid
color :White to Pale Beige
CAS DataBase Reference :1092364-38-9
Boiling point :629.7±55.0 °C(Predicted)
Density :1.409±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka :5.35±0.30(Predicted)
form :Solid
color :White to Pale Beige
CAS DataBase Reference :1092364-38-9
Safety Information
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Description
Poziotinib (HM781-36B) is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Phase 2.Related product price
- PD 0325901
₹15891.1-60457.63 - 4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE
₹11539.45-46547.5 - Dacomitinib (PF299804)
₹5000-14200
