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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >protein tyrosine kinase >PD168393

PD168393

PD168393 Structure
  • ₹11539.45 - ₹46547.5
  • Product name: PD168393
  • CAS: 194423-15-9
  • MF: C17H13BrN4O
  • MW: 369.22
  • EINECS:
  • MDL Number:MFCD02179207
  • Synonyms:4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;PD 168393;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;PD168393;PD-168393;PD 168393;CS-2316;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0285
  • Product descriptionPD168393 ≥98% (HPLC)
  • Packaging5MG
  • Price₹11539.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number513033
  • Product descriptionPD 168393 - CAS 194423-15-9 - Calbiochem A potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC?? = 700 pM).
  • Packaging1MG
  • Price₹25430
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0285
  • Product descriptionPD168393 ≥98% (HPLC)
  • Packaging25MG
  • Price₹46547.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PZ0285 PD168393 ≥98% (HPLC) 5MG ₹11539.45 2022-06-14 Buy
Sigma-Aldrich(India) 513033 PD 168393 - CAS 194423-15-9 - Calbiochem A potent, cell-permeable, irreversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC?? = 700 pM). 1MG ₹25430 2022-06-14 Buy
Sigma-Aldrich(India) PZ0285 PD168393 ≥98% (HPLC) 25MG ₹46547.5 2022-06-14 Buy

Properties

Melting point :279℃
Boiling point :571.1±50.0 °C(Predicted)
Density :1.558±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO
form :powder
pka :12.19±0.43(Predicted)
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
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Description

PD 168393 is a potent, irreversible, cell-permeable and selective inhibitor of EGFR (epidermal growth factor receptor). Does not inhibit any other protein kinases. PD 168393 binds to the catalytic domain of the EGFR (EGF receptor tyrosine kinase) with a 1:1 stoichiometry and alkylating Cys773.

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