PD153035 HCl
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- ₹8500 - ₹38117.4
- Product name: PD153035 HCl
- CAS: 183322-45-4
- MF: C16H14BrN3O2.HCl
- MW: 0
- EINECS:
- MDL Number:MFCD01074805
- Synonyms:PD 153035 hydrochloride, >=98%;SU-5271 (AG1517) HCl ,ZM 252868 HCl;6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride PD153035;4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-, monohydrochloride;6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride;N-(3-BroMophenyl)-6,7-diMethoxyquinazolin-4-aMine hydrochloride;ZM 252868;PD153035 (HCl salt)
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberB4945
- Product descriptionPD 153035 Hydrochloride
- Packaging25MG
- Price₹8500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberB4945
- Product descriptionPD 153035 Hydrochloride
- Packaging100MG
- Price₹14800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0564
- Product descriptionPD153035 hydrochloride ≥98% (HPLC)
- Packaging5MG
- Price₹9423.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0564
- Product descriptionPD153035 hydrochloride ≥98% (HPLC)
- Packaging25MG
- Price₹38117.4
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | B4945 | PD 153035 Hydrochloride | 25MG | ₹8500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B4945 | PD 153035 Hydrochloride | 100MG | ₹14800 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | SML0564 | PD153035 hydrochloride ≥98% (HPLC) | 5MG | ₹9423.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0564 | PD153035 hydrochloride ≥98% (HPLC) | 25MG | ₹38117.4 | 2022-06-14 | Buy |
Properties
Melting point :265°C(lit.)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||||||||||||||||
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Description
Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR) has been associated with cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. PD 153035 is a highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM; IC50 = 29 pM). It has been shown to rapidly suppress autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells, as well as to selectively block EGF-mediated cellular processes, including mitogenesis and early gene expression.Related product price
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