DAPH
- ₹16562.25 - ₹74346.1
- Product name: DAPH
- CAS: 145915-58-8
- MF: C20H15N3O2
- MW: 329.35
- EINECS:406-050-3
- MDL Number:MFCD00236442
- Synonyms:DAPH/CGP 52411;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411;DAPH-1 (DAPH;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;DAPH >=98% (HPLC), solid
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberD3943
- Product descriptionDAPH ≥98% (HPLC), solid
- Packaging5MG
- Price₹16562.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD3943
- Product descriptionDAPH ≥98% (HPLC), solid
- Packaging25MG
- Price₹74346.1
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D3943 | DAPH ≥98% (HPLC), solid | 5MG | ₹16562.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D3943 | DAPH ≥98% (HPLC), solid | 25MG | ₹74346.1 | 2022-06-14 | Buy |
Properties
Melting point :199-202℃
Density :1.374
storage temp. :2-8°C
solubility :DMSO: ~30 mg/mL
pka :9.06±0.20(Predicted)
form :solid
color :orange
Density :1.374
storage temp. :2-8°C
solubility :DMSO: ~30 mg/mL
pka :9.06±0.20(Predicted)
form :solid
color :orange
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
DAPH is a tyrosine kinase inhibitor, which suppresses and reverses the formation of Aβ42 fibers in neurons. DAPH displays specificity towards the EGFR kinase3 receptor. Studies suggest that DAPH can attenuate phenylephrine-induced endothelium contraction in aortic rings. It is known that Aβ42 proteins are composed of β sheets that are arranged parallel to the fibril axis and are several micrometers in length. DAPH is a useful tool in inhibiting these proteins because it can disrupt fibril formation which is vital for β sheet formation.Related product price
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