Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

DAPH

DAPH Structure
  • ₹16562.25 - ₹74346.1
  • Product name: DAPH
  • CAS: 145915-58-8
  • MF: C20H15N3O2
  • MW: 329.35
  • EINECS:406-050-3
  • MDL Number:MFCD00236442
  • Synonyms:DAPH/CGP 52411;4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411;DAPH-1 (DAPH;1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-;DAPH >=98% (HPLC), solid
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3943
  • Product descriptionDAPH ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹16562.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3943
  • Product descriptionDAPH ≥98% (HPLC), solid
  • Packaging25MG
  • Price₹74346.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D3943 DAPH ≥98% (HPLC), solid 5MG ₹16562.25 2022-06-14 Buy
Sigma-Aldrich(India) D3943 DAPH ≥98% (HPLC), solid 25MG ₹74346.1 2022-06-14 Buy

Properties

Melting point :199-202℃
Density :1.374
storage temp. :2-8°C
solubility :DMSO: ~30 mg/mL
pka :9.06±0.20(Predicted)
form :solid
color :orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

DAPH is a tyrosine kinase inhibitor, which suppresses and reverses the formation of Aβ42 fibers in neurons. DAPH displays specificity towards the EGFR kinase3 receptor. Studies suggest that DAPH can attenuate phenylephrine-induced endothelium contraction in aortic rings. It is known that Aβ42 proteins are composed of β sheets that are arranged parallel to the fibril axis and are several micrometers in length. DAPH is a useful tool in inhibiting these proteins because it can disrupt fibril formation which is vital for β sheet formation.

Related product price