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ChemicalBook > Product Catalogue >API >Circulatory system drugs >ACE inhibitor >LCZ696 InteMediate

LCZ696 InteMediate

LCZ696 InteMediate Structure
  • ₹0
  • Product name: LCZ696 InteMediate
  • CAS: 1426129-50-1
  • MF: C20H25NO3
  • MW: 327.42
  • EINECS:202-804-9
  • MDL Number:MFCD28359221
  • Synonyms:tert-butyl (R)-(1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate;1)(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate;N-[(1R)-2-[1,1'-Biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester;LCZ696 InteMediate;(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbaMate;LCZ696 InteMediate USP/EP/BP;N-[(1R)-2-[1,1’-biphenyl]-4-yl-1-(hydroxymethyl)ethyl]carbamic acid;(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-y...
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :514.5±50.0 °C(Predicted)
Density :1.103±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :11.85±0.46(Predicted)
InChI :InChI=1S/C20H25NO3/c1-20(2,3)24-19(23)21-18(14-22)13-15-9-11-17(12-10-15)16-7-5-4-6-8-16/h4-12,18,22H,13-14H2,1-3H3,(H,21,23)/t18-/m1/s1
InChIKey :TYQICOFAZDVKMK-GOSISDBHSA-N
SMILES :C(OC(C)(C)C)(=O)N[C@@H](CO)CC1=CC=C(C2=CC=CC=C2)C=C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-?[(1R)?-?2-?[1,?1''-?Biphenyl]?-?4-?yl-?1-?(hydroxymethyl)?ethyl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is a useful intermediate for preparing Sacubitril (S080900)/Valsartan (V095750).