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ChemicalBook > Product Catalogue >API >Digestive system drugs >Antacid and Mucosal protective Drugs >Lansoprazole

Lansoprazole

Lansoprazole Structure
  • ₹5400 - ₹18727.25
  • Product name: Lansoprazole
  • CAS: 103577-45-3
  • MF: C16H14F3N3O2S
  • MW: 369.36
  • EINECS:2017-001-1
  • MDL Number:MFCD00866873
  • Synonyms:LANSOPRAZOLE, MM(CRM STANDARD);LANSOPRAZOLE USP(CRM STANDARD);2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz ;OGAST;LANSOPRAZOLE;LANSAPRAZOLE;LANSOX;LANZOR
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberL0233
  • Product descriptionLansoprazole
  • Packaging1G
  • Price₹5400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberL0233
  • Product descriptionLansoprazole
  • Packaging5G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL8533
  • Product descriptionLansoprazole ≥98% (TLC), powder
  • Packaging250MG
  • Price₹6841.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1390
  • Product descriptionLansoprazole Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8270.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberL8533
  • Product descriptionLansoprazole ≥98% (TLC), powder
  • Packaging1G
  • Price₹18727.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) L0233 Lansoprazole 1G ₹5400 2022-05-26 Buy
TCI Chemicals (India) L0233 Lansoprazole 5G ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) L8533 Lansoprazole ≥98% (TLC), powder 250MG ₹6841.4 2022-06-14 Buy
Sigma-Aldrich(India) PHR1390 Lansoprazole Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8270.3 2022-06-14 Buy
Sigma-Aldrich(India) L8533 Lansoprazole ≥98% (TLC), powder 1G ₹18727.25 2022-06-14 Buy

Properties

Melting point :178-182°C dec.
Boiling point :555.8±60.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in anhydrous ethanol, very slightly soluble in acetonitrile.
pka :pKa 2.34±0.37 (Occasionally);3.53±0.37 (Occasionally);8.48±0.30 (Occasionally)
form :powder
color :off-white
Merck :14,5362
BCS Class :2
InChIKey :MJIHNNLFOKEZEW-UHFFFAOYSA-N
CAS DataBase Reference :103577-45-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lansoprazole is a proton pump inhibitor that inactivates the hydrogen/potassium-stimulated ATPase pumps in parietal cells, thus inhibiting gastric acid secretion and increasing intragastric pH. A substituted benzimidazole, it binds covalently to proton pumps, providing complete and prolonged inhibition of acid secretion. Pharmacokinetic properties include a time of maximal plasma concentration after oral administration (Tmax) of 1.2 - 2.1 hours, and an oral bioavailability of 80-90%. Lansoprazole is metabolized by several human cytochrome P450s, most prominently by CYP2C19 and CYP3A4.

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Suppliers and manufacturers

Jigs Chemical ltd SGMR PHARMACEUTICALS PVT LTD ANWITA APIS Micro Orgo Chem J S LABS HEMA LABORATORIES Vivimed Labs Ltd Enal Drugs Pvt Ltd Honour Lab Limited Lee Pharma Ltd