Leflunomide
- ₹2000 - ₹28848.63
- Product name: Leflunomide
- CAS: 75706-12-6
- MF: C12H9F3N2O2
- MW: 270.21
- EINECS:616-254-6
- MDL Number:MFCD00867593
- Synonyms:LEFLUNOMIDE;HWA 486;ALPHA,ALPHA,ALPHA-TRIFLUORO-5-METHYL-4-ISOXAZOLECARBOXY-P-TOLUIDIDE;5-METHYLISOXAZOLE-4-(4-TRIFLUOROMETHYLCARBOXANILIDE);5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-4-ISOXAZOLECARBOXAMIDE;N-(4-TRIFLUOROMETHYLPHENYL)-5-METHYLISOXAZOL-4-CARBOXAMIDE;5-methylisoxazole-4-carboxylicacid(4-trifluoromethyl)anilide ;5-methyl-n-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamid
5 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 25MG
- 100MG
- 200MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberL0250
- Product descriptionLeflunomide
- Packaging200MG
- Price₹2000
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0250
- Product descriptionLeflunomide
- Packaging1G
- Price₹7400
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL5025
- Product descriptionLeflunomide Immunosuppressant
- Packaging25MG
- Price₹8952.28
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1378
- Product descriptionLeflunomide Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging1G
- Price₹9093
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberL5025
- Product descriptionLeflunomide Immunosuppressant
- Packaging100MG
- Price₹28848.63
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | L0250 | Leflunomide | 200MG | ₹2000 | 2022-05-26 | Buy |
TCI Chemicals (India) | L0250 | Leflunomide | 1G | ₹7400 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | L5025 | Leflunomide Immunosuppressant | 25MG | ₹8952.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1378 | Leflunomide Pharmaceutical Secondary Standard; Certified Reference Material | 1G | ₹9093 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | L5025 | Leflunomide Immunosuppressant | 100MG | ₹28848.63 | 2022-06-14 | Buy |
Properties
Melting point :166.5 °C
Boiling point :289.3±40.0 °C(Predicted)
Density :1.392±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in methanol, sparingly soluble in methylene chloride.
form :Solid
pka :10.8(at 25℃)
color :White
Merck :14,5432
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :VHOGYURTWQBHIL-UHFFFAOYSA-N
CAS DataBase Reference :75706-12-6(CAS DataBase Reference)
Boiling point :289.3±40.0 °C(Predicted)
Density :1.392±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in methanol, sparingly soluble in methylene chloride.
form :Solid
pka :10.8(at 25℃)
color :White
Merck :14,5432
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
InChIKey :VHOGYURTWQBHIL-UHFFFAOYSA-N
CAS DataBase Reference :75706-12-6(CAS DataBase Reference)
Safety Information
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Description
Leflunomide is a synthetic isoxazol derivative that regulates T lymphocyte progression through the cell cycle by selectively inhibiting de novo pyrimidine synthesis. As a prodrug, it is rapidly converted to its active open ring metabolite, A-771726 , which inhibits human lymphocyte proliferation with an IC50 value of 12.5 μM, in vitro. Leflunomide has been evaluated in phase II and III clinical trials for efficacy in slowing the disease progression of rheumatoid arthritis. It has also been used as an immunosuppressant agent to prevent rejection of transplant allografts and xenografts.More related product prices
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