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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Thyroid hormone and antithyroid drugs >Levothyroxine sodium

Levothyroxine sodium

Levothyroxine sodium Structure
  • ₹0
  • Product name: Levothyroxine sodium
  • CAS: 55-03-8
  • MF: C15H12I4NNaO4
  • MW: 800.87
  • EINECS:200-221-4
  • MDL Number:MFCD00149110
  • Synonyms:Levothyroxine sodium;Sodium 4-O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine;(S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionic Acid odium;(s)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionic acid sodium salt;sodium (s)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propionate;L-THYROXINE SODIUM ANHYDROUS;Levothyroxine Sdium;levothyroxine sodium anhydrous
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :207-210 (dec.)(lit.)
alpha :D20 -4.4° (c = 3 in 70% ethanol)
Density :d420 2.381
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :cell culture medium: 0.1 mg/mL
form :powder
color :Off-white to light yellow
BCS Class :1,3
Stability :Hygroscopic
InChIKey :JMHCCAYJTTWMCX-QWPJCUCISA-M
EPA Substance Registry System :Levothyroxine sodium (55-03-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.

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Suppliers and manufacturers

Lupin Ltd Apotex Pharmachem India Pvt Ltd Gland Pharma Ltd Biophore India Pharmaceuticals Pvt Ltd Opulent Pharma Globofarm International Private Limited Abil Chempharma Pvt. Ltd. Dazzle Corporation TCI Chemicals (India) Pvt. Ltd. AZICO BIOPHORE INDIA PVT LTD