Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Lisinopril

Lisinopril

Lisinopril Structure
  • ₹0
  • Product name: Lisinopril
  • CAS: 76547-98-3
  • MF: C21H31N3O5
  • MW: 405.49
  • EINECS:278-488-1
  • MDL Number:MFCD00214086
  • Synonyms:(S)-1-[(S)-6-AMINO-2-((S)-1-CARBOXY-3-PHENYL-PROPYLAMINO)-HEXANOYL]-PYRROLIDINE-2-CARBOXYLIC ACID;TENSOPRIL;VIVATEC;ZESTRIL;mk522 ;PRINIL;PRINIVIL;n-{n-[(s)-1-carboxy-3-phenylpropyl]-l-lysyl}-l-proline
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :162-165 °C
Boiling point :666.4±55.0 °C(Predicted)
Density :1.251±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: ≥10 mg/mL
form :solid
pka :2.18±0.10(Predicted)
color :white
BCS Class :3
CAS DataBase Reference :76547-98-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Angiotensin-converting enzyme (ACE) removes the C-terminal dipeptide from angiotensin I to form angiotensin II, a powerful vasoconstrictor. ACE is a key regulator of the renin-angiotensin system and an important drug target for the treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications in diabetes. Lisinopril is a potent ACE inhibitor that blocks the formation of angiotensin I with an IC50 value of 1.2 nM (ovine) and displays ID50 values of 2.3 and 6.5 μg/kg in rat and canine, respectively. At 0.1 nM lisinopril reduces the formation of endothelin-1 and increases nitric oxide in human vascular endothelial cells.

More related product prices

L-Lysine DL-Lysine acetylsalicylate D-Pyrrolidine-2-carboxylic acid Lisinopril 84793-24-8 N2-(1S-Ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysine Lisinopril

Related product price

Suppliers and manufacturers

J S LABS Lupin Ltd Alfa Omega Pharma Sunmoon Pharmaceuticals Pvt Ltd Unimark Remedies Ltd Hetero Drugs Limited EMCURE PHARMACEUTICALS LTD CLEARSYNTH LABS LTD. A.J Chemicals UNIMARK REMEDIES LTD