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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >Loganin

Loganin

Loganin Structure
  • ₹7000 - ₹38970
  • Product name: Loganin
  • CAS: 18524-94-2
  • MF: C17H26O10
  • MW: 390.38
  • EINECS:242-398-0
  • MDL Number:MFCD00075645
  • Synonyms:Loganin, >=98%;methyl [1S-(1alpha,4aalpha,6alpha,7alpha,7a.alpha.)]-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methylcyclopenta[c]pyran-4-carboxylate ;LOGANIN hplc;Methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-Methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)oxan-2-yl]oxy}-1H,4aH,5H,6H,7H,7aH-cyclopenta[c]pyran-4-carboxylate;LOGANIN;LOGANINE;methyl 1-(beta-D-glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-c;Cyclopenta[c]pyran-4-carboxylic acid, 1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, [1S-(1alpha,4aalpha,6alpha,7alpha,7aalpha)]
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberL0268
  • Product descriptionLoganin
  • Packaging10MG
  • Price₹7000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberL0268
  • Product descriptionLoganin
  • Packaging50MG
  • Price₹10400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number36483
  • Product descriptionLoganin analytical standard
  • Packaging10MG
  • Price₹38970
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) L0268 Loganin 10MG ₹7000 2022-05-26 Buy
TCI Chemicals (India) L0268 Loganin 50MG ₹10400 2022-05-26 Buy
Sigma-Aldrich(India) 36483 Loganin analytical standard 10MG ₹38970 2022-06-14 Buy

Properties

Melting point :222°C
alpha :D20 -82.1° (water)
Boiling point :608.8±55.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
Water Solubility :Completely soluble in water
solubility :DMF: 15 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
form :Solid
pka :12.80±0.70(Predicted)
color :White to Almost white
λmax :240nm(MeOH)(lit.)
Merck :14,5560
BRN :55724
InChIKey :AMBQHHVBBHTQBF-UHFFFAOYSA-N
LogP :-2.730 (est)
CAS DataBase Reference :18524-94-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Loganin, an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent free-radical-scavenging activity and inhibitory effects on melanogenesis. Research has shown that Loganin also down-regulates mRNA expression of caspase-3, caspase-9, receptor activator for nuclear factor κ B ligand (RANKL) and up-regulates bcl-2 expression. Experimental studies suggest that Loganin can increase contents of osteocalcin and collagen type I and also improve activity of alkaline phosphatase.

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