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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Loperamide

Loperamide

Loperamide Structure
  • ₹51527
  • Product name: Loperamide
  • CAS: 106900-12-3
  • MF: C29H33ClN2O3
  • MW: 493.04
  • EINECS:
  • MDL Number:MFCD00870596
  • Synonyms:loperamide oxide;R 58425;trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutanamide 1-oxide;trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-oxide monohydrate;4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide N-oxide;LoperaMide-d6 N-Oxide;Loperamide EP Impurity F;Loperamide impurity-F(EP)
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2916
  • Product descriptionLoperamide Related Compound F pharmaceutical secondary standard, certified reference material
  • Packaging50MG
  • Price₹51527
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR2916 Loperamide Related Compound F pharmaceutical secondary standard, certified reference material 50MG ₹51527 2022-06-14 Buy

Properties

solubility :Practically insoluble in water, freely soluble in alcohol and in methylene chloride.
pka :12.94±0.20(Predicted)
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Labelled Loperamide oxide (LOPOX). It is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon.

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