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MANOALIDE

MANOALIDE Structure
  • ₹0
  • Product name: MANOALIDE
  • CAS: 75088-80-1
  • MF: C25H36O5
  • MW: 416.55
  • EINECS:
  • MDL Number:MFCD00153826
  • Synonyms:MANOALIDE;MANOALIDE, LUFFARIELLA VARIABILIS;4-[3,6-DIHYDRO-6-HYDROXY-5-[4-METHYL-6-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-3-HEXENYL]-2H-PYRAN-2-YL]-5-HYDROXY-2(5H)-FURANONE;(5R)-4-[(2R,6R)-3,6-Dihydro-6-hydroxy-5-[4-methyl-6-(2,6,6-trimethyl-1-cyclohexene-1-yl)-3-hexenyl]-2H-pyran-2-yl]-5-hydroxyfuran-2(5H)-one;2(5H)-Furanone, 4-((2R,6R)-3,6-dihydro-6-hydroxy-5-((3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenyl)-2H-pyran-2-yl)-5-hydroxy-, (5R)-;2(5H)-Furanone, 4-(3,6-dihydro-6-hydroxy-5-(4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenyl)-2H-pyran-2-yl)-5-hydroxy-;2(5H)-Furanone, 4-[(2R,6R)-3,6-dihydro-6-hydroxy-5-[(3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexen-1-yl]-2H-pyran-2-yl]-5-hydroxy-, (5R)-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :609.6±55.0 °C(Predicted)
Density :1.133±0.06 g/cm3(Predicted)
storage temp. :−20°C
form :oil
pka :9.75±0.40(Predicted)
color :tan
LogP :5.190 (est)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Manoalide is a natural sesterterpenoid which irreversibly inhibits secretory phospholipase A2 isoforms from human synovium, bee venom, and cobra venom (IC50 values are 3.9, 7.5, and 2 μM, respectively). It also potently blocks calcium channels (IC50 = 1 μM) and inhibits phospholipase C (IC50 = 1.5 μM). Manoalide can be used in biochemical, cellular, and in vivo experiments.

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Suppliers and manufacturers

Aladdin Scientific TargetMol Chemicals Inc. 3B Scientific Corporation Kainic.com 3B Scientific Corporation Fluorochem Ltd City Chemical LLC Advance Scientific & Chemical UK GREEN SCIENTIFIC CO.,LIMITED MOLEKULA Ltd.